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Consumer product exposures associated with urinary phthalate levels in pregnant women.

Publication ,  Journal Article
Buckley, JP; Palmieri, RT; Matuszewski, JM; Herring, AH; Baird, DD; Hartmann, KE; Hoppin, JA
Published in: Journal of exposure science & environmental epidemiology
September 2012

Human phthalate exposure is ubiquitous, but little is known regarding predictors of urinary phthalate levels. To explore this, 50 pregnant women aged 18-38 years completed two questionnaires on potential phthalate exposures and provided a first morning void. Urine samples were analyzed for 12 phthalate metabolites. Associations with questionnaire items were evaluated via Wilcoxon tests and t-tests, and r-squared values were calculated in multiple linear regression models. Few measured factors were statistically significantly associated with phthalate levels. Individuals who used nail polish had higher levels of mono-butyl phthalate (P=0.048) than non-users. Mono-benzyl phthalate levels were higher among women who used eye makeup (P=0.034) or used makeup on a regular basis (P=0.004). Women who used cologne or perfume had higher levels of di-(2-ethylhexyl) phthalate metabolites. Household products, home flooring or paneling, and other personal care products were also associated with urinary phthalates. The proportion of variance in metabolite concentrations explained by questionnaire items ranged between 0.31 for mono-ethyl phthalate and 0.42 for mono-n-methyl phthalate. Although personal care product use may be an important predictor of urinary phthalate levels, most of the variability in phthalate exposure was not captured by our relatively comprehensive set of questionnaire items.

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Published In

Journal of exposure science & environmental epidemiology

DOI

EISSN

1559-064X

ISSN

1559-0631

Publication Date

September 2012

Volume

22

Issue

5

Start / End Page

468 / 475

Related Subject Headings

  • Young Adult
  • Surveys and Questionnaires
  • Pregnancy
  • Phthalic Acids
  • Perfume
  • Humans
  • Household Products
  • Household Articles
  • Female
  • Epidemiology
 

Citation

APA
Chicago
ICMJE
MLA
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Buckley, J. P., Palmieri, R. T., Matuszewski, J. M., Herring, A. H., Baird, D. D., Hartmann, K. E., & Hoppin, J. A. (2012). Consumer product exposures associated with urinary phthalate levels in pregnant women. Journal of Exposure Science & Environmental Epidemiology, 22(5), 468–475. https://doi.org/10.1038/jes.2012.33
Buckley, Jessie P., Rachel T. Palmieri, Jeanine M. Matuszewski, Amy H. Herring, Donna D. Baird, Katherine E. Hartmann, and Jane A. Hoppin. “Consumer product exposures associated with urinary phthalate levels in pregnant women.Journal of Exposure Science & Environmental Epidemiology 22, no. 5 (September 2012): 468–75. https://doi.org/10.1038/jes.2012.33.
Buckley JP, Palmieri RT, Matuszewski JM, Herring AH, Baird DD, Hartmann KE, et al. Consumer product exposures associated with urinary phthalate levels in pregnant women. Journal of exposure science & environmental epidemiology. 2012 Sep;22(5):468–75.
Buckley, Jessie P., et al. “Consumer product exposures associated with urinary phthalate levels in pregnant women.Journal of Exposure Science & Environmental Epidemiology, vol. 22, no. 5, Sept. 2012, pp. 468–75. Epmc, doi:10.1038/jes.2012.33.
Buckley JP, Palmieri RT, Matuszewski JM, Herring AH, Baird DD, Hartmann KE, Hoppin JA. Consumer product exposures associated with urinary phthalate levels in pregnant women. Journal of exposure science & environmental epidemiology. 2012 Sep;22(5):468–475.

Published In

Journal of exposure science & environmental epidemiology

DOI

EISSN

1559-064X

ISSN

1559-0631

Publication Date

September 2012

Volume

22

Issue

5

Start / End Page

468 / 475

Related Subject Headings

  • Young Adult
  • Surveys and Questionnaires
  • Pregnancy
  • Phthalic Acids
  • Perfume
  • Humans
  • Household Products
  • Household Articles
  • Female
  • Epidemiology