Bench-to-bedside: The use of local anesthetics to attenuate inflammation in acute respiratory distress syndrome.
Publication
, Journal Article
Krishnamoorthy, V; Chung, L
Published in: Int J Crit Illn Inj Sci
April 2014
The acute respiratory distress syndrome (ARDS) remains a world-wide treatment challenge, with high morbidity and mortality. The central pathophysiology of ARDS centers around inflammation in the lung and increased microvascular permeability. Local anesthetics have been shown to have anti-inflammatory effects at the basic science level and the advent of local anesthetics with improved cardiovascular safety profiles has made use of local anesthetics in attenuating the inflammation in ARDS a recent research interest. In this review, we will provide a brief summary of some of the basic science work in local anesthetics and lung inflammation and provide a case for the bench to bedside research in this potential therapy.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Int J Crit Illn Inj Sci
DOI
ISSN
2229-5151
Publication Date
April 2014
Volume
4
Issue
2
Start / End Page
98 / 100
Location
India
Related Subject Headings
- 4206 Public health
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Krishnamoorthy, V., & Chung, L. (2014). Bench-to-bedside: The use of local anesthetics to attenuate inflammation in acute respiratory distress syndrome. Int J Crit Illn Inj Sci, 4(2), 98–100. https://doi.org/10.4103/2229-5151.134143
Krishnamoorthy, Vijay, and Linda Chung. “Bench-to-bedside: The use of local anesthetics to attenuate inflammation in acute respiratory distress syndrome.” Int J Crit Illn Inj Sci 4, no. 2 (April 2014): 98–100. https://doi.org/10.4103/2229-5151.134143.
Krishnamoorthy V, Chung L. Bench-to-bedside: The use of local anesthetics to attenuate inflammation in acute respiratory distress syndrome. Int J Crit Illn Inj Sci. 2014 Apr;4(2):98–100.
Krishnamoorthy, Vijay, and Linda Chung. “Bench-to-bedside: The use of local anesthetics to attenuate inflammation in acute respiratory distress syndrome.” Int J Crit Illn Inj Sci, vol. 4, no. 2, Apr. 2014, pp. 98–100. Pubmed, doi:10.4103/2229-5151.134143.
Krishnamoorthy V, Chung L. Bench-to-bedside: The use of local anesthetics to attenuate inflammation in acute respiratory distress syndrome. Int J Crit Illn Inj Sci. 2014 Apr;4(2):98–100.
Published In
Int J Crit Illn Inj Sci
DOI
ISSN
2229-5151
Publication Date
April 2014
Volume
4
Issue
2
Start / End Page
98 / 100
Location
India
Related Subject Headings
- 4206 Public health
- 3202 Clinical sciences