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The Performance and Association Between Patient-reported and Performance-based Measures of Physical Functioning in Research on Individuals with Arthritis.

Publication ,  Journal Article
Pinheiro, LC; Callahan, LF; Cleveland, RJ; Edwards, LJ; Reeve, BB
Published in: J Rheumatol
January 2016

OBJECTIVE: To evaluate the association between patient-reported outcome (PRO) and performance-based (PB) measures of physical functioning (PF) among individuals with self-identified arthritis to inform decisions of which to use when evaluating the effectiveness of a physical activity intervention. METHODS: Secondary data analysis of a nonrandomized 2-arm pre-post community trial of 462 individuals who self-identified as having arthritis and participated in the Walk with Ease (WWE) intervention. Two PRO and 8 PB assessments were collected at baseline (preintervention) and at 6-week followup. We calculated correlations between PB and PRO measures, assessed how measures identified changes in PF from baseline to followup, and compared PRO and PB measures to arthritis symptoms of pain, stiffness, and fatigue. RESULTS: Strength of correlations between PB and PRO measures varied depending on the PB measure, ranging from 0.21 to 0.54. PRO and PB measures identified PF improvements from baseline to followup, but none showed significant differences between the 2 WWE modalities (instructor-led or self-directed groups). Correlations with arthritis symptoms were stronger for PRO (0.30-0.46) than PB measures (0.03-0.31). CONCLUSION: PRO measures may provide us with insights into aspects of PF that are not identified by PB measures alone. Use of PRO measures allows patients to communicate their perceptions of PF, which may provide a more accurate representation of overall PF. Our study does not suggest abandoning the use of PB measures to characterize PF in patients with self-identified arthritis, but recommends that PRO measures may serve as complementary or surrogate endpoints for some studies.

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Published In

J Rheumatol

DOI

EISSN

1499-2752

Publication Date

January 2016

Volume

43

Issue

1

Start / End Page

131 / 137

Location

Canada

Related Subject Headings

  • Walking
  • Task Performance and Analysis
  • Severity of Illness Index
  • Sensitivity and Specificity
  • Self Report
  • Retrospective Studies
  • Range of Motion, Articular
  • Pain Measurement
  • Motor Activity
  • Middle Aged
 

Citation

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Pinheiro, L. C., Callahan, L. F., Cleveland, R. J., Edwards, L. J., & Reeve, B. B. (2016). The Performance and Association Between Patient-reported and Performance-based Measures of Physical Functioning in Research on Individuals with Arthritis. J Rheumatol, 43(1), 131–137. https://doi.org/10.3899/jrheum.150432
Pinheiro, Laura C., Leigh F. Callahan, Rebecca J. Cleveland, Lloyd J. Edwards, and Bryce B. Reeve. “The Performance and Association Between Patient-reported and Performance-based Measures of Physical Functioning in Research on Individuals with Arthritis.J Rheumatol 43, no. 1 (January 2016): 131–37. https://doi.org/10.3899/jrheum.150432.
Pinheiro, Laura C., et al. “The Performance and Association Between Patient-reported and Performance-based Measures of Physical Functioning in Research on Individuals with Arthritis.J Rheumatol, vol. 43, no. 1, Jan. 2016, pp. 131–37. Pubmed, doi:10.3899/jrheum.150432.

Published In

J Rheumatol

DOI

EISSN

1499-2752

Publication Date

January 2016

Volume

43

Issue

1

Start / End Page

131 / 137

Location

Canada

Related Subject Headings

  • Walking
  • Task Performance and Analysis
  • Severity of Illness Index
  • Sensitivity and Specificity
  • Self Report
  • Retrospective Studies
  • Range of Motion, Articular
  • Pain Measurement
  • Motor Activity
  • Middle Aged