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Pilot Study to Describe the Trajectory of Symptoms and Adaptive Strategies of Adults Living with Low-grade Glioma.

Publication ,  Journal Article
Affronti, ML; Randazzo, D; Lipp, ES; Peters, KB; Herndon, SC; Woodring, S; Healy, P; Cone, CK; Herndon, JE; Schneider, SM
Published in: Semin Oncol Nurs
December 2018

OBJECTIVES: To describe the adaptability to the patterns in symptoms and quality of life (QoL) during 6 months post low-grade glioma diagnosis by valid and reliable tools; to identify through qualitative interviews patient/provider adaptive techniques and strategies; and to assess associations among patient characteristics, symptoms and QoL, and adaptive techniques or strategies. DATA SOURCES: Demographic, clinical and pathologic data from medical records. Validated instruments that assess QoL, fatigue, depression, and distress were completed at 2, 4, and 6 months post diagnosis. Qualitative interviews identifying the symptoms, challenges, adaptive techniques and strategies were conducted at 4 and 6 months. CONCLUSION: The most frequently used adaptive strategies included: obtaining community support (87%), managing expectations (73%) and support systems (67%), and seeking out knowledge about physical (67%) and behavioral symptoms (53%). Seizures were reported with IDH1mut (11%) but not IDH1wildtype. Patients with either IDH1mut or TERTmut consistently reported lower QoL and higher distress, depression, and fatigue scores. IDH1/TERTmut may be related to lower QoL because of IDH1mut-related seizures. IMPLICATIONS FOR NURSING PRACTICE: Findings provide a list of adaptive strategies and characteristics to address the problems and symptoms that may improve overall QoL in patients with low-grade glioma.

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Published In

Semin Oncol Nurs

DOI

EISSN

1878-3449

Publication Date

December 2018

Volume

34

Issue

5

Start / End Page

472 / 485

Location

United States

Related Subject Headings

  • Quality of Life
  • Pilot Projects
  • Nursing
  • Middle Aged
  • Male
  • Humans
  • Glioma
  • Female
  • Brain Neoplasms
  • Aged, 80 and over
 

Citation

APA
Chicago
ICMJE
MLA
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Affronti, M. L., Randazzo, D., Lipp, E. S., Peters, K. B., Herndon, S. C., Woodring, S., … Schneider, S. M. (2018). Pilot Study to Describe the Trajectory of Symptoms and Adaptive Strategies of Adults Living with Low-grade Glioma. Semin Oncol Nurs, 34(5), 472–485. https://doi.org/10.1016/j.soncn.2018.10.006
Affronti, Mary Lou, Dina Randazzo, Eric S. Lipp, Katherine B. Peters, Susan C. Herndon, Sarah Woodring, Patrick Healy, Christina K. Cone, James E. Herndon, and Susan M. Schneider. “Pilot Study to Describe the Trajectory of Symptoms and Adaptive Strategies of Adults Living with Low-grade Glioma.Semin Oncol Nurs 34, no. 5 (December 2018): 472–85. https://doi.org/10.1016/j.soncn.2018.10.006.
Affronti ML, Randazzo D, Lipp ES, Peters KB, Herndon SC, Woodring S, et al. Pilot Study to Describe the Trajectory of Symptoms and Adaptive Strategies of Adults Living with Low-grade Glioma. Semin Oncol Nurs. 2018 Dec;34(5):472–85.
Affronti, Mary Lou, et al. “Pilot Study to Describe the Trajectory of Symptoms and Adaptive Strategies of Adults Living with Low-grade Glioma.Semin Oncol Nurs, vol. 34, no. 5, Dec. 2018, pp. 472–85. Pubmed, doi:10.1016/j.soncn.2018.10.006.
Affronti ML, Randazzo D, Lipp ES, Peters KB, Herndon SC, Woodring S, Healy P, Cone CK, Herndon JE, Schneider SM. Pilot Study to Describe the Trajectory of Symptoms and Adaptive Strategies of Adults Living with Low-grade Glioma. Semin Oncol Nurs. 2018 Dec;34(5):472–485.
Journal cover image

Published In

Semin Oncol Nurs

DOI

EISSN

1878-3449

Publication Date

December 2018

Volume

34

Issue

5

Start / End Page

472 / 485

Location

United States

Related Subject Headings

  • Quality of Life
  • Pilot Projects
  • Nursing
  • Middle Aged
  • Male
  • Humans
  • Glioma
  • Female
  • Brain Neoplasms
  • Aged, 80 and over