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Antidepressant drug therapy in psychotic depression.

Publication ,  Journal Article
Davidson, JR; McLeod, MN; Kurland, AA; White, HL
Published in: Br J Psychiatry
November 1977

Imipramine and phenelzine were ineffective in the treatment of five primary unipolar depressives with delusions, even when plasma levels of imipramine and desmethylimipramine or activity of platelet monoamine oxidase suggested that an adequate dose of drug had been given. Four patients went on to receive ECT and all responded well. Five non-delusional patients responded satisfactorily to the antidepressant drug given. Nine out of ten subjects were women. Non-delusional patients showed some placebo response. ECT is considered to be the treatment of choice in the acute phase of delusional depression in women.

Duke Scholars

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Published In

Br J Psychiatry

DOI

ISSN

0007-1250

Publication Date

November 1977

Volume

131

Start / End Page

493 / 496

Location

England

Related Subject Headings

  • Psychotic Disorders
  • Psychiatry
  • Phenelzine
  • Monoamine Oxidase
  • Middle Aged
  • Male
  • Imipramine
  • Humans
  • Female
  • Drug Evaluation
 

Citation

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Davidson, J. R., McLeod, M. N., Kurland, A. A., & White, H. L. (1977). Antidepressant drug therapy in psychotic depression. Br J Psychiatry, 131, 493–496. https://doi.org/10.1192/bjp.131.5.493
Davidson, J. R., M. N. McLeod, A. A. Kurland, and H. L. White. “Antidepressant drug therapy in psychotic depression.Br J Psychiatry 131 (November 1977): 493–96. https://doi.org/10.1192/bjp.131.5.493.
Davidson JR, McLeod MN, Kurland AA, White HL. Antidepressant drug therapy in psychotic depression. Br J Psychiatry. 1977 Nov;131:493–6.
Davidson, J. R., et al. “Antidepressant drug therapy in psychotic depression.Br J Psychiatry, vol. 131, Nov. 1977, pp. 493–96. Pubmed, doi:10.1192/bjp.131.5.493.
Davidson JR, McLeod MN, Kurland AA, White HL. Antidepressant drug therapy in psychotic depression. Br J Psychiatry. 1977 Nov;131:493–496.
Journal cover image

Published In

Br J Psychiatry

DOI

ISSN

0007-1250

Publication Date

November 1977

Volume

131

Start / End Page

493 / 496

Location

England

Related Subject Headings

  • Psychotic Disorders
  • Psychiatry
  • Phenelzine
  • Monoamine Oxidase
  • Middle Aged
  • Male
  • Imipramine
  • Humans
  • Female
  • Drug Evaluation