A Novel 18 F-Labeling Method for the Synthesis of [ 18 F]-Piperidine-Containing Ligands as Potential PET Radiotracers for σ Receptors
Publication
, Journal Article
Ortiz, GX; Chansaenpak, K; Wang, M; Ma, X; Wang, H; Li, Z; Wang, Q
Published in: Synlett
March 1, 2018
We report a novel 18 F-labeling method for the preparation of 18 F-containing piperidine derivatives. This method is demonstrated on the design and synthesis of 18 F-labeled potential PET radiotracers of σ receptors for initial biological evaluations. 1 Introduction 2 Design and Synthesis of Novel [ 19 F]-3 and [ 19 F]-3′ 3 Radiosynthesis of Novel [ 18 F]-3 and [ 18 F]-3′ 4 In vivo Uptake and Pharmacokinetics of [ 18 F]-3 and [ 18 F]-3′ 5 Conclusion.
Duke Scholars
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Published In
Synlett
DOI
EISSN
1437-2096
ISSN
0936-5214
Publication Date
March 1, 2018
Volume
29
Issue
4
Start / End Page
410 / 414
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry
Citation
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Chicago
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MLA
NLM
Ortiz, G. X., Chansaenpak, K., Wang, M., Ma, X., Wang, H., Li, Z., & Wang, Q. (2018). A Novel 18 F-Labeling Method for the Synthesis of [ 18 F]-Piperidine-Containing Ligands as Potential PET Radiotracers for σ Receptors. Synlett, 29(4), 410–414. https://doi.org/10.1055/s-0036-1591734
Ortiz, G. X., K. Chansaenpak, M. Wang, X. Ma, H. Wang, Z. Li, and Q. Wang. “A Novel 18 F-Labeling Method for the Synthesis of [ 18 F]-Piperidine-Containing Ligands as Potential PET Radiotracers for σ Receptors.” Synlett 29, no. 4 (March 1, 2018): 410–14. https://doi.org/10.1055/s-0036-1591734.
Ortiz GX, Chansaenpak K, Wang M, Ma X, Wang H, Li Z, et al. A Novel 18 F-Labeling Method for the Synthesis of [ 18 F]-Piperidine-Containing Ligands as Potential PET Radiotracers for σ Receptors. Synlett. 2018 Mar 1;29(4):410–4.
Ortiz, G. X., et al. “A Novel 18 F-Labeling Method for the Synthesis of [ 18 F]-Piperidine-Containing Ligands as Potential PET Radiotracers for σ Receptors.” Synlett, vol. 29, no. 4, Mar. 2018, pp. 410–14. Scopus, doi:10.1055/s-0036-1591734.
Ortiz GX, Chansaenpak K, Wang M, Ma X, Wang H, Li Z, Wang Q. A Novel 18 F-Labeling Method for the Synthesis of [ 18 F]-Piperidine-Containing Ligands as Potential PET Radiotracers for σ Receptors. Synlett. 2018 Mar 1;29(4):410–414.
Published In
Synlett
DOI
EISSN
1437-2096
ISSN
0936-5214
Publication Date
March 1, 2018
Volume
29
Issue
4
Start / End Page
410 / 414
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry