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Breaking or making immunological privilege in the central nervous system: the regulation of immunity by neuropeptides.

Publication ,  Journal Article
Reinke, E; Fabry, Z
Published in: Immunology letters
April 2006

Immune privilege in the central nervous system (CNS) is not maintained by immune ignorance of the CNS, but by CNS control over inflammatory processes. In this review we examine the role neuropeptides play in maintenance of immune privilege in the CNS. Vasoactive intestinal peptide, alpha-melanocyte-stimulating-hormone, neuropeptide Y, and somatostatin are members of an anti-inflammatory repertoire of immune modulators, while substance P acts to break immune privilege and promote inflammation in the CNS. Here we focus both on cellular responses to these neuropeptides and the role these peptides play in immune privilege as it relates to CNS autoimmunity.

Duke Scholars

Published In

Immunology letters

DOI

EISSN

1879-0542

ISSN

0165-2478

Publication Date

April 2006

Volume

104

Issue

1-2

Start / End Page

102 / 109

Related Subject Headings

  • Neuropeptides
  • Mice
  • Immunology
  • Immunity
  • Central Nervous System
  • Animals
  • 3204 Immunology
  • 1107 Immunology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Reinke, E., & Fabry, Z. (2006). Breaking or making immunological privilege in the central nervous system: the regulation of immunity by neuropeptides. Immunology Letters, 104(1–2), 102–109. https://doi.org/10.1016/j.imlet.2005.11.009
Reinke, Emily, and Zsuzsa Fabry. “Breaking or making immunological privilege in the central nervous system: the regulation of immunity by neuropeptides.Immunology Letters 104, no. 1–2 (April 2006): 102–9. https://doi.org/10.1016/j.imlet.2005.11.009.
Reinke, Emily, and Zsuzsa Fabry. “Breaking or making immunological privilege in the central nervous system: the regulation of immunity by neuropeptides.Immunology Letters, vol. 104, no. 1–2, Apr. 2006, pp. 102–09. Epmc, doi:10.1016/j.imlet.2005.11.009.
Journal cover image

Published In

Immunology letters

DOI

EISSN

1879-0542

ISSN

0165-2478

Publication Date

April 2006

Volume

104

Issue

1-2

Start / End Page

102 / 109

Related Subject Headings

  • Neuropeptides
  • Mice
  • Immunology
  • Immunity
  • Central Nervous System
  • Animals
  • 3204 Immunology
  • 1107 Immunology