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Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease.

Publication ,  Journal Article
Gilgor, RS; Chiaramonti, A; Goldsmith, LA; Lazarus, GS
Published in: Cutis
April 1980

A new synthetic oral retinoid, 13-cis retinoic acid, is fairly well tolerated in patients and appears to be effective in those with Darier's disease and lamellar ichthyosis. It is less effective in those with pityriasis rubra pilaris. The mechanism of action of 13-cis retinoic acid in disorders of keratinization is unknown at the present time; however, it does not appear to cause lysosomal proliferation in therapeutic doses.

Duke Scholars

Published In

Cutis

ISSN

0011-4162

Publication Date

April 1980

Volume

25

Issue

4

Start / End Page

380 / 385

Location

United States

Related Subject Headings

  • Tretinoin
  • Pityriasis Rubra Pilaris
  • Middle Aged
  • Male
  • Isotretinoin
  • Ichthyosis
  • Humans
  • Female
  • Evaluation Studies as Topic
  • Dose-Response Relationship, Drug
 

Citation

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Gilgor, R. S., Chiaramonti, A., Goldsmith, L. A., & Lazarus, G. S. (1980). Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease. Cutis, 25(4), 380–385.
Gilgor, R. S., A. Chiaramonti, L. A. Goldsmith, and G. S. Lazarus. “Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease.Cutis 25, no. 4 (April 1980): 380–85.
Gilgor RS, Chiaramonti A, Goldsmith LA, Lazarus GS. Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease. Cutis. 1980 Apr;25(4):380–5.
Gilgor, R. S., et al. “Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease.Cutis, vol. 25, no. 4, Apr. 1980, pp. 380–85.
Gilgor RS, Chiaramonti A, Goldsmith LA, Lazarus GS. Evaluation of 13-cis retinoic acid in lamellar ichthyosis, pityriasis rubra pilaris and Darier's disease. Cutis. 1980 Apr;25(4):380–385.

Published In

Cutis

ISSN

0011-4162

Publication Date

April 1980

Volume

25

Issue

4

Start / End Page

380 / 385

Location

United States

Related Subject Headings

  • Tretinoin
  • Pityriasis Rubra Pilaris
  • Middle Aged
  • Male
  • Isotretinoin
  • Ichthyosis
  • Humans
  • Female
  • Evaluation Studies as Topic
  • Dose-Response Relationship, Drug