
Alkenylation of C(sp3 )-H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts.
Publication
, Journal Article
Liu, C; Wang, Q
Published in: Angewandte Chemie (International ed. in English)
April 2018
α-Vinylation of phosphonates, phosphine oxides, sulfones, sulfonamides, and sulfoxides has been achieved by selective C-H zincation and copper-catalyzed C(sp3 )-C(sp2 ) cross-coupling reaction using vinylphenyliodonium salts. The vinylation transformation proceeds in high efficiency and stereospecificity under mild reaction conditions. This zincative cross-coupling reaction represents a general alkenylation strategy, which is also applicable for α-alkenylation of esters, amides, and nitriles in the synthesis of β,γ-unsaturated carbonyl compounds.
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Published In
Angewandte Chemie (International ed. in English)
DOI
EISSN
1521-3773
ISSN
1433-7851
Publication Date
April 2018
Volume
57
Issue
17
Start / End Page
4727 / 4731
Related Subject Headings
- Zinc
- Stereoisomerism
- Salts
- Organophosphonates
- Organic Chemistry
- Molecular Structure
- Hydrocarbons, Iodinated
- Copper
- Catalysis
- Alkylation
Citation
APA
Chicago
ICMJE
MLA
NLM
Liu, C., & Wang, Q. (2018). Alkenylation of C(sp3 )-H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts. Angewandte Chemie (International Ed. in English), 57(17), 4727–4731. https://doi.org/10.1002/anie.201713278
Liu, Chuan, and Qiu Wang. “Alkenylation of C(sp3 )-H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts.” Angewandte Chemie (International Ed. in English) 57, no. 17 (April 2018): 4727–31. https://doi.org/10.1002/anie.201713278.
Liu C, Wang Q. Alkenylation of C(sp3 )-H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts. Angewandte Chemie (International ed in English). 2018 Apr;57(17):4727–31.
Liu, Chuan, and Qiu Wang. “Alkenylation of C(sp3 )-H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts.” Angewandte Chemie (International Ed. in English), vol. 57, no. 17, Apr. 2018, pp. 4727–31. Epmc, doi:10.1002/anie.201713278.
Liu C, Wang Q. Alkenylation of C(sp3 )-H Bonds by Zincation/Copper-Catalyzed Cross-Coupling with Iodonium Salts. Angewandte Chemie (International ed in English). 2018 Apr;57(17):4727–4731.

Published In
Angewandte Chemie (International ed. in English)
DOI
EISSN
1521-3773
ISSN
1433-7851
Publication Date
April 2018
Volume
57
Issue
17
Start / End Page
4727 / 4731
Related Subject Headings
- Zinc
- Stereoisomerism
- Salts
- Organophosphonates
- Organic Chemistry
- Molecular Structure
- Hydrocarbons, Iodinated
- Copper
- Catalysis
- Alkylation