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Changes in Medical Management after Coronary CT Angiography.

Publication ,  Journal Article
Naue, VM; Camargo, G; Sabioni, LR; Lima, RDSL; Derenne, ME; Lorenzo, ARD; Freire, MDC; Azevedo Filho, CF; Resende, ES; Gottlieb, I
Published in: Arquivos brasileiros de cardiologia
October 2015

Coronary computed tomography angiography (CCTA) allows for non-invasive coronary artery disease (CAD) phenotyping. There are still some uncertainties regarding the impact this knowledge has on the clinical care of patients.To determine whether CAD phenotyping by CCTA influences clinical decision making by the prescription of cardiovascular drugs and their impact on non-LDL cholesterol (NLDLC) levels.We analysed consecutive patients from 2008 to 2011 submitted to CCTA without previous diagnosis of CAD that had two serial measures of NLDLC, one up to 3 months before CCTA and the second from 3 to 6 months after.A total of 97 patients were included, of which 69% were men, mean age 64 ± 12 years. CCTA revealed that 18 (18%) patients had no CAD, 38 (39%) had non-obstructive (< 50%) lesions and 41 (42%) had at least one obstructive ≥ 50% lesion. NLDLC was similar at baseline between the grups (138 ± 52 mg/dL vs. 135 ± 42 mg/dL vs. 131 ± 44 mg/dL, respectively, p = 0.32). We found significative reduction in NLDLC among patients with obstrctive lesions (-18%, p = 0.001). We also found a positive relationship between clinical treatment intensification with aspirin and cholesterol reducing drugs and the severity of CAD.Our data suggest that CCTA results were used for cardiovascular clinical treatment titration, with especial intensification seen in patients with obstructive ≥50% CAD.

Published In

Arquivos brasileiros de cardiologia

DOI

EISSN

1678-4170

ISSN

0066-782X

Publication Date

October 2015

Volume

105

Issue

4

Start / End Page

410 / 417

Related Subject Headings

  • Tomography, X-Ray Computed
  • Statistics, Nonparametric
  • Severity of Illness Index
  • Risk Factors
  • Retrospective Studies
  • Platelet Aggregation Inhibitors
  • Middle Aged
  • Male
  • Humans
  • Female
 

Citation

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Naue, V. M., Camargo, G., Sabioni, L. R., Lima, R. D. S. L., Derenne, M. E., Lorenzo, A. R. D., … Gottlieb, I. (2015). Changes in Medical Management after Coronary CT Angiography. Arquivos Brasileiros de Cardiologia, 105(4), 410–417. https://doi.org/10.5935/abc.20150088
Naue, Vânia Mairi, Gabriel Camargo, Letícia Roberto Sabioni, Ronaldo de Souza Leão Lima, Maria Eduarda Derenne, Andréa Rocha de Lorenzo, Monica Di Calafiori Freire, Clério Francisco Azevedo Filho, Elmiro Santos Resende, and Ilan Gottlieb. “Changes in Medical Management after Coronary CT Angiography.Arquivos Brasileiros de Cardiologia 105, no. 4 (October 2015): 410–17. https://doi.org/10.5935/abc.20150088.
Naue VM, Camargo G, Sabioni LR, Lima RDSL, Derenne ME, Lorenzo ARD, et al. Changes in Medical Management after Coronary CT Angiography. Arquivos brasileiros de cardiologia. 2015 Oct;105(4):410–7.
Naue, Vânia Mairi, et al. “Changes in Medical Management after Coronary CT Angiography.Arquivos Brasileiros de Cardiologia, vol. 105, no. 4, Oct. 2015, pp. 410–17. Epmc, doi:10.5935/abc.20150088.
Naue VM, Camargo G, Sabioni LR, Lima RDSL, Derenne ME, Lorenzo ARD, Freire MDC, Azevedo Filho CF, Resende ES, Gottlieb I. Changes in Medical Management after Coronary CT Angiography. Arquivos brasileiros de cardiologia. 2015 Oct;105(4):410–417.

Published In

Arquivos brasileiros de cardiologia

DOI

EISSN

1678-4170

ISSN

0066-782X

Publication Date

October 2015

Volume

105

Issue

4

Start / End Page

410 / 417

Related Subject Headings

  • Tomography, X-Ray Computed
  • Statistics, Nonparametric
  • Severity of Illness Index
  • Risk Factors
  • Retrospective Studies
  • Platelet Aggregation Inhibitors
  • Middle Aged
  • Male
  • Humans
  • Female