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Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial.

Publication ,  Journal Article
Carter, T; Guo, B; Turner, D; Morres, I; Khalil, E; Brighton, E; Armstrong, M; Callaghan, P
Published in: BMC Psychiatry
October 14, 2015

BACKGROUND: Exercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the effectiveness of a preferred intensity exercise intervention on the depressive symptoms of adolescents with depression. METHODS: We randomly assigned 87 adolescents who were receiving treatment for depression to either 12 sessions of aerobic exercise at preferred intensity alongside treatment as usual or treatment as usual only. The primary outcome was depressive symptom change using the Children's Depression Inventory 2(nd) Version (CDI-2) at post intervention. Secondary outcomes were health-related quality of life and physical activity rates. Outcomes were taken at baseline, post intervention and at six month follow up. RESULTS: CDI-2 score reduction did not differ significantly between groups at post-intervention (est. 95% CI -6.82, 1.68, p = 0.23). However, there was a difference in CDI-2 score reduction at six month follow-up in favour of the intervention of -4.81 (est. 95% CI -9.49, -0.12, p = 0.03). Health-related quality of life and physical activity rates did not differ significantly between groups at post-intervention and follow-up. CONCLUSIONS: There was no additional effect of preferred intensity exercise alongside treatment as usual on depressive reduction immediately post intervention. However, effects were observed at six months post-intervention, suggesting a delayed response. However, further trials, with larger samples are required to determine the validity of this finding. TRIAL REGISTRATION: ClinicalTrials.gov NCT01474837, March 16 2011.

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Published In

BMC Psychiatry

DOI

EISSN

1471-244X

Publication Date

October 14, 2015

Volume

15

Start / End Page

247

Location

England

Related Subject Headings

  • Quality of Life
  • Psychiatry
  • Outcome Assessment, Health Care
  • Mental Health Services
  • Male
  • Humans
  • Female
  • Exercise Therapy
  • Depression
  • Adolescent
 

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Carter, T., Guo, B., Turner, D., Morres, I., Khalil, E., Brighton, E., … Callaghan, P. (2015). Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial. BMC Psychiatry, 15, 247. https://doi.org/10.1186/s12888-015-0638-z
Carter, Tim, Boliang Guo, David Turner, Ioannis Morres, Elizabeth Khalil, Emily Brighton, Marie Armstrong, and Patrick Callaghan. “Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial.BMC Psychiatry 15 (October 14, 2015): 247. https://doi.org/10.1186/s12888-015-0638-z.
Carter T, Guo B, Turner D, Morres I, Khalil E, Brighton E, et al. Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial. BMC Psychiatry. 2015 Oct 14;15:247.
Carter, Tim, et al. “Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial.BMC Psychiatry, vol. 15, Oct. 2015, p. 247. Pubmed, doi:10.1186/s12888-015-0638-z.
Carter T, Guo B, Turner D, Morres I, Khalil E, Brighton E, Armstrong M, Callaghan P. Preferred intensity exercise for adolescents receiving treatment for depression: a pragmatic randomised controlled trial. BMC Psychiatry. 2015 Oct 14;15:247.
Journal cover image

Published In

BMC Psychiatry

DOI

EISSN

1471-244X

Publication Date

October 14, 2015

Volume

15

Start / End Page

247

Location

England

Related Subject Headings

  • Quality of Life
  • Psychiatry
  • Outcome Assessment, Health Care
  • Mental Health Services
  • Male
  • Humans
  • Female
  • Exercise Therapy
  • Depression
  • Adolescent