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Poor Oral Health Linked with Increased Risk of Infectious Complications in Adults with Leukemia.

Publication ,  Journal Article
Allareddy, V; Prakasam, S; Allareddy, V; Martinez-Schlurmann, NI; Rampa, S; Nalliah, RP; Eswaran, SVK; Elangovan, S
Published in: J Mass Dent Soc
2015

OBJECTIVE: The objective of this study is to examine the impact of the presence of gingivitis/periodontitis on the occurrence of infectious complications (including septicemia, bacterial infections, and mycoses) in hospitalized leukemic adults in the United States. METHODS: A retrospective analysis of the Nationwide Inpatient Sample (NIS) for the years 2004-2010 was performed. All hospitalized leukemic patients aged 18 to 65 years were selected. The association between occurrence of gingivitis/periodontitis and infectious complications was examined by multivariable logistic regression models. A total of 135,692 hospitalizations were due to leukemias during the study period. Among these, gingivitis/periodontitis was present in 0.6%. Septicemia occurred in 27.8% of those who had gingivitis/periodontitis (compared to 19.6% in those without gingivitis/periodontitis), bacterial infections occurred in 19.5% of those who had gingivitis/periodontitis (compared to 10.1% in those without gingivitis/periodontitis), and mycoses occurred in 20.7% of those who had gingivitis/periodontitis (compared to 10.7% in those without gingivitis/periodontitis). Patients who had gingivitis/periodontitis were associated with significantly higher odds for septicemia (OR = 1.58, 95% CI = 1.14-2.19, p = 0.01), bacterial infections (OR = 2.15, 95% CI = 1.51-3.07, p<0.01), mycoses (OR = 2.16, 95% CI = 1.43-3.28, p<0.01), or any infectious complication (OR = 2.15, 95% CI = 1.63-2.84, p<0.01) when compared to their counterparts following adjustment for multiple patient and hospital-level confounding factors. CONCLUSIONS: Poor oral health (as defined by the presence of gingivitis/periodontitis) is an independent predictor of increased risk of infectious complications in hospitalized leukemic adults in the United States.

Duke Scholars

Published In

J Mass Dent Soc

ISSN

0025-4800

Publication Date

2015

Volume

64

Issue

3

Start / End Page

38 / 42

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Sepsis
  • Retrospective Studies
  • Prevalence
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Periodontitis
  • Oral Health
  • Opportunistic Infections
  • Mycoses
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Allareddy, V., Prakasam, S., Martinez-Schlurmann, N. I., Rampa, S., Nalliah, R. P., Eswaran, S. V. K., & Elangovan, S. (2015). Poor Oral Health Linked with Increased Risk of Infectious Complications in Adults with Leukemia. J Mass Dent Soc, 64(3), 38–42.
Allareddy, Veerasathpurush, Sivaraman Prakasam, Veerajalandhar Allareddy, Natalia I. Martinez-Schlurmann, Sankeerth Rampa, Romesh P. Nalliah, Sridhar V. K. Eswaran, and Satheesh Elangovan. “Poor Oral Health Linked with Increased Risk of Infectious Complications in Adults with Leukemia.J Mass Dent Soc 64, no. 3 (2015): 38–42.
Allareddy V, Prakasam S, Martinez-Schlurmann NI, Rampa S, Nalliah RP, Eswaran SVK, et al. Poor Oral Health Linked with Increased Risk of Infectious Complications in Adults with Leukemia. J Mass Dent Soc. 2015;64(3):38–42.
Allareddy, Veerasathpurush, et al. “Poor Oral Health Linked with Increased Risk of Infectious Complications in Adults with Leukemia.J Mass Dent Soc, vol. 64, no. 3, 2015, pp. 38–42.
Allareddy V, Prakasam S, Martinez-Schlurmann NI, Rampa S, Nalliah RP, Eswaran SVK, Elangovan S. Poor Oral Health Linked with Increased Risk of Infectious Complications in Adults with Leukemia. J Mass Dent Soc. 2015;64(3):38–42.

Published In

J Mass Dent Soc

ISSN

0025-4800

Publication Date

2015

Volume

64

Issue

3

Start / End Page

38 / 42

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Sepsis
  • Retrospective Studies
  • Prevalence
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Periodontitis
  • Oral Health
  • Opportunistic Infections
  • Mycoses