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Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice.

Publication ,  Journal Article
McMillen, BA; DaVanzo, EA; Song, AH; Scott, SM; Rodriguez, ME
Published in: Eur J Pharmacol
January 24, 1989

A series of classical, atypical and putative antipsychotic drugs were compared for their ability to inhibit isolation-induced intraspecies aggression with affinity for D-2 dopamine receptors and induction of akinesia. The majority of drugs tested significantly inhibited aggressive behavior only after doses that greatly decreased the ability of mice to move. Even though akinesia seemed to account for inhibition of aggression there was no apparent correlation with binding to striatal D-2 receptors.

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Published In

Eur J Pharmacol

DOI

ISSN

0014-2999

Publication Date

January 24, 1989

Volume

160

Issue

1

Start / End Page

149 / 153

Location

Netherlands

Related Subject Headings

  • Social Isolation
  • Pharmacology & Pharmacy
  • Movement Disorders
  • Mice
  • Male
  • Dopamine Antagonists
  • Corpus Striatum
  • Behavioral Science & Comparative Psychology
  • Antipsychotic Agents
  • Animals
 

Citation

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McMillen, B. A., DaVanzo, E. A., Song, A. H., Scott, S. M., & Rodriguez, M. E. (1989). Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice. Eur J Pharmacol, 160(1), 149–153. https://doi.org/10.1016/0014-2999(89)90664-x
McMillen, B. A., E. A. DaVanzo, A. H. Song, S. M. Scott, and M. E. Rodriguez. “Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice.Eur J Pharmacol 160, no. 1 (January 24, 1989): 149–53. https://doi.org/10.1016/0014-2999(89)90664-x.
McMillen BA, DaVanzo EA, Song AH, Scott SM, Rodriguez ME. Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice. Eur J Pharmacol. 1989 Jan 24;160(1):149–53.
McMillen, B. A., et al. “Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice.Eur J Pharmacol, vol. 160, no. 1, Jan. 1989, pp. 149–53. Pubmed, doi:10.1016/0014-2999(89)90664-x.
McMillen BA, DaVanzo EA, Song AH, Scott SM, Rodriguez ME. Effects of classical and atypical antipsychotic drugs on isolation-induced aggression in male mice. Eur J Pharmacol. 1989 Jan 24;160(1):149–153.
Journal cover image

Published In

Eur J Pharmacol

DOI

ISSN

0014-2999

Publication Date

January 24, 1989

Volume

160

Issue

1

Start / End Page

149 / 153

Location

Netherlands

Related Subject Headings

  • Social Isolation
  • Pharmacology & Pharmacy
  • Movement Disorders
  • Mice
  • Male
  • Dopamine Antagonists
  • Corpus Striatum
  • Behavioral Science & Comparative Psychology
  • Antipsychotic Agents
  • Animals