Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel

Digital pathology in nephrology clinical trials, research, and pathology practice.

Publication ,  Journal Article
Barisoni, L; Hodgin, JB
Published in: Curr Opin Nephrol Hypertens
November 2017

PURPOSE OF REVIEW: In this review, we will discuss (i) how the recent advancements in digital technology and computational engineering are currently applied to nephropathology in the setting of clinical research, trials, and practice; (ii) the benefits of the new digital environment; (iii) how recognizing its challenges provides opportunities for transformation; and (iv) nephropathology in the upcoming era of kidney precision and predictive medicine. RECENT FINDINGS: Recent studies highlighted how new standardized protocols facilitate the harmonization of digital pathology database infrastructure and morphologic, morphometric, and computer-aided quantitative analyses. Digital pathology enables robust protocols for clinical trials and research, with the potential to identify previously underused or unrecognized clinically useful parameters. The integration of digital pathology with molecular signatures is leading the way to establishing clinically relevant morpho-omic taxonomies of renal diseases. SUMMARY: The introduction of digital pathology in clinical research and trials, and the progressive implementation of the modern software ecosystem, opens opportunities for the development of new predictive diagnostic paradigms and computer-aided algorithms, transforming the practice of renal disease into a modern computational science.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Curr Opin Nephrol Hypertens

DOI

EISSN

1473-6543

Publication Date

November 2017

Volume

26

Issue

6

Start / End Page

450 / 459

Location

England

Related Subject Headings

  • Urology & Nephrology
  • Telemedicine
  • Software
  • Precision Medicine
  • Pathology
  • Nephrology
  • Microscopy
  • Kidney Diseases
  • Kidney
  • Image Processing, Computer-Assisted
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Barisoni, L., & Hodgin, J. B. (2017). Digital pathology in nephrology clinical trials, research, and pathology practice. Curr Opin Nephrol Hypertens, 26(6), 450–459. https://doi.org/10.1097/MNH.0000000000000360
Barisoni, Laura, and Jeffrey B. Hodgin. “Digital pathology in nephrology clinical trials, research, and pathology practice.Curr Opin Nephrol Hypertens 26, no. 6 (November 2017): 450–59. https://doi.org/10.1097/MNH.0000000000000360.
Barisoni L, Hodgin JB. Digital pathology in nephrology clinical trials, research, and pathology practice. Curr Opin Nephrol Hypertens. 2017 Nov;26(6):450–9.
Barisoni, Laura, and Jeffrey B. Hodgin. “Digital pathology in nephrology clinical trials, research, and pathology practice.Curr Opin Nephrol Hypertens, vol. 26, no. 6, Nov. 2017, pp. 450–59. Pubmed, doi:10.1097/MNH.0000000000000360.
Barisoni L, Hodgin JB. Digital pathology in nephrology clinical trials, research, and pathology practice. Curr Opin Nephrol Hypertens. 2017 Nov;26(6):450–459.

Published In

Curr Opin Nephrol Hypertens

DOI

EISSN

1473-6543

Publication Date

November 2017

Volume

26

Issue

6

Start / End Page

450 / 459

Location

England

Related Subject Headings

  • Urology & Nephrology
  • Telemedicine
  • Software
  • Precision Medicine
  • Pathology
  • Nephrology
  • Microscopy
  • Kidney Diseases
  • Kidney
  • Image Processing, Computer-Assisted