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Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology.

Publication ,  Journal Article
Barisoni, L; Gimpel, C; Kain, R; Laurinavicius, A; Bueno, G; Zeng, C; Liu, Z; Schaefer, F; Kretzler, M; Holzman, LB; Hewitt, SM
Published in: Clinical kidney journal
April 2017

The introduction of digital pathology to nephrology provides a platform for the development of new methodologies and protocols for visual, morphometric and computer-aided assessment of renal biopsies. Application of digital imaging to pathology made substantial progress over the past decade; it is now in use for education, clinical trials and translational research. Digital pathology evolved as a valuable tool to generate comprehensive structural information in digital form, a key prerequisite for achieving precision pathology for computational biology. The application of this new technology on an international scale is driving novel methods for collaborations, providing unique opportunities but also challenges. Standardization of methods needs to be rigorously evaluated and applied at each step, from specimen processing to scanning, uploading into digital repositories, morphologic, morphometric and computer-aided assessment, data collection and analysis. In this review, we discuss the status and opportunities created by the application of digital imaging to precision nephropathology, and present a vision for the near future.

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Published In

Clinical kidney journal

DOI

EISSN

2048-8513

ISSN

2048-8505

Publication Date

April 2017

Volume

10

Issue

2

Start / End Page

176 / 187

Related Subject Headings

  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Barisoni, L., Gimpel, C., Kain, R., Laurinavicius, A., Bueno, G., Zeng, C., … Hewitt, S. M. (2017). Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology. Clinical Kidney Journal, 10(2), 176–187. https://doi.org/10.1093/ckj/sfw129
Barisoni, Laura, Charlotte Gimpel, Renate Kain, Arvydas Laurinavicius, Gloria Bueno, Caihong Zeng, Zhihong Liu, et al. “Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology.Clinical Kidney Journal 10, no. 2 (April 2017): 176–87. https://doi.org/10.1093/ckj/sfw129.
Barisoni L, Gimpel C, Kain R, Laurinavicius A, Bueno G, Zeng C, et al. Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology. Clinical kidney journal. 2017 Apr;10(2):176–87.
Barisoni, Laura, et al. “Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology.Clinical Kidney Journal, vol. 10, no. 2, Apr. 2017, pp. 176–87. Epmc, doi:10.1093/ckj/sfw129.
Barisoni L, Gimpel C, Kain R, Laurinavicius A, Bueno G, Zeng C, Liu Z, Schaefer F, Kretzler M, Holzman LB, Hewitt SM. Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology. Clinical kidney journal. 2017 Apr;10(2):176–187.
Journal cover image

Published In

Clinical kidney journal

DOI

EISSN

2048-8513

ISSN

2048-8505

Publication Date

April 2017

Volume

10

Issue

2

Start / End Page

176 / 187

Related Subject Headings

  • 3202 Clinical sciences