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Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization.

Publication ,  Journal Article
Leak Bryant, A; Gosselin, T; Coffman, EM; Phillips, B; Gray, TF; Knafl, GJ; Klepin, HD; Wood, WA; Muss, H; Reeve, BB
Published in: Oncol Nurs Forum
September 1, 2018

OBJECTIVES: To examine longitudinal symptoms, mobility and function, and quality of life (QOL) in adults newly diagnosed with acute leukemia. SAMPLE & SETTING: 55 adults undergoing induction chemotherapy at the University of North Carolina Lineberger Comprehensive Cancer Center and the Duke Cancer Institute. METHODS & VARIABLES: A prospective, longitudinal study with measures of mobility and function, global physical and mental health, cancer-related fatigue, anxiety, depression, sleep disturbance, pain intensity, and leukemia-specific QOL was conducted. Data were analyzed using descriptive statistics, linear mixed modeling, and one-way analysis of variance. RESULTS: 49 adults with acute leukemia completed assessments during hospitalizations. Global mental health and pain intensity did not change significantly. Global physical health significantly improved. Fatigue, anxiety, depression, and sleep disturbance decreased significantly. QOL increased significantly. IMPLICATIONS FOR NURSING: The significant decrease in anxiety and fatigue during hospitalization may be attributable to understanding of the disease process, familiarity with the staff, and ability to communicate concerns.

Duke Scholars

Published In

Oncol Nurs Forum

DOI

EISSN

1538-0688

Publication Date

September 1, 2018

Volume

45

Issue

5

Start / End Page

653 / 664

Location

United States

Related Subject Headings

  • Young Adult
  • Quality of Life
  • Prospective Studies
  • Nursing
  • North Carolina
  • Mobility Limitation
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Leukemia, Myeloid, Acute
 

Citation

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ICMJE
MLA
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Leak Bryant, A., Gosselin, T., Coffman, E. M., Phillips, B., Gray, T. F., Knafl, G. J., … Reeve, B. B. (2018). Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization. Oncol Nurs Forum, 45(5), 653–664. https://doi.org/10.1188/18.ONF.653-664
Leak Bryant, Ashley, Tracy Gosselin, Erin M. Coffman, Brett Phillips, Tamryn F. Gray, George J. Knafl, Heidi D. Klepin, William A. Wood, Hyman Muss, and Bryce B. Reeve. “Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization.Oncol Nurs Forum 45, no. 5 (September 1, 2018): 653–64. https://doi.org/10.1188/18.ONF.653-664.
Leak Bryant A, Gosselin T, Coffman EM, Phillips B, Gray TF, Knafl GJ, et al. Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization. Oncol Nurs Forum. 2018 Sep 1;45(5):653–64.
Leak Bryant, Ashley, et al. “Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization.Oncol Nurs Forum, vol. 45, no. 5, Sept. 2018, pp. 653–64. Pubmed, doi:10.1188/18.ONF.653-664.
Leak Bryant A, Gosselin T, Coffman EM, Phillips B, Gray TF, Knafl GJ, Klepin HD, Wood WA, Muss H, Reeve BB. Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization. Oncol Nurs Forum. 2018 Sep 1;45(5):653–664.

Published In

Oncol Nurs Forum

DOI

EISSN

1538-0688

Publication Date

September 1, 2018

Volume

45

Issue

5

Start / End Page

653 / 664

Location

United States

Related Subject Headings

  • Young Adult
  • Quality of Life
  • Prospective Studies
  • Nursing
  • North Carolina
  • Mobility Limitation
  • Middle Aged
  • Male
  • Longitudinal Studies
  • Leukemia, Myeloid, Acute