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Culture-negative prosthetic valve endocarditis with concomitant septicemia due to a nontoxigenic Corynebacterium diphtheriae biotype gravis isolate in a patient with multiple risk factors.

Publication ,  Journal Article
Clinton, LK; Bankowski, MJ; Shimasaki, T; Sae-Ow, W; Whelen, AC; O'Connor, N; Kim, W; Young, R
Published in: J Clin Microbiol
November 2013

A 54-year-old female with a prosthetic mitral valve presented with a 3-day history of dizziness, subjective fever, and chills. Blood cultures were positive for a pleomorphic Gram-positive rod. Initial phenotypic testing could only support the identification of a Corynebacterium species. Nucleic acid sequencing (16S rRNA) and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) were conclusive for Corynebacterium diphtheriae. Definitive phenotypic testing classified the strain as nontoxigenic C. diphtheriae biotype Gravis.

Duke Scholars

Published In

J Clin Microbiol

DOI

EISSN

1098-660X

Publication Date

November 2013

Volume

51

Issue

11

Start / End Page

3900 / 3902

Location

United States

Related Subject Headings

  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Sepsis
  • Risk Factors
  • RNA, Ribosomal, 16S
  • Prosthesis-Related Infections
  • Molecular Sequence Data
  • Middle Aged
  • Microbiology
  • Microbial Sensitivity Tests
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Clinton, L. K., Bankowski, M. J., Shimasaki, T., Sae-Ow, W., Whelen, A. C., O’Connor, N., … Young, R. (2013). Culture-negative prosthetic valve endocarditis with concomitant septicemia due to a nontoxigenic Corynebacterium diphtheriae biotype gravis isolate in a patient with multiple risk factors. J Clin Microbiol, 51(11), 3900–3902. https://doi.org/10.1128/JCM.01403-13
Clinton, Lani Kai, Matthew J. Bankowski, Teppei Shimasaki, Wichit Sae-Ow, A Christian Whelen, Norman O’Connor, Wesley Kim, and Royden Young. “Culture-negative prosthetic valve endocarditis with concomitant septicemia due to a nontoxigenic Corynebacterium diphtheriae biotype gravis isolate in a patient with multiple risk factors.J Clin Microbiol 51, no. 11 (November 2013): 3900–3902. https://doi.org/10.1128/JCM.01403-13.
Clinton, Lani Kai, et al. “Culture-negative prosthetic valve endocarditis with concomitant septicemia due to a nontoxigenic Corynebacterium diphtheriae biotype gravis isolate in a patient with multiple risk factors.J Clin Microbiol, vol. 51, no. 11, Nov. 2013, pp. 3900–02. Pubmed, doi:10.1128/JCM.01403-13.
Clinton LK, Bankowski MJ, Shimasaki T, Sae-Ow W, Whelen AC, O’Connor N, Kim W, Young R. Culture-negative prosthetic valve endocarditis with concomitant septicemia due to a nontoxigenic Corynebacterium diphtheriae biotype gravis isolate in a patient with multiple risk factors. J Clin Microbiol. 2013 Nov;51(11):3900–3902.

Published In

J Clin Microbiol

DOI

EISSN

1098-660X

Publication Date

November 2013

Volume

51

Issue

11

Start / End Page

3900 / 3902

Location

United States

Related Subject Headings

  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Sepsis
  • Risk Factors
  • RNA, Ribosomal, 16S
  • Prosthesis-Related Infections
  • Molecular Sequence Data
  • Middle Aged
  • Microbiology
  • Microbial Sensitivity Tests
  • Humans