Skip to main content
Journal cover image

Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy".

Publication ,  Journal Article
Sherertz, EF; Jegasothy, BV; Lazarus, GS
Published in: J Am Acad Dermatol
January 1985

In this report we describe the successful outcome following the use of corticosteroid pulse therapy in a patient with a severe phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Steroid pulse therapy may be lifesaving in a severe dermatosis, such as toxic epidermal necrolysis.

Duke Scholars

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

January 1985

Volume

12

Issue

1 Pt 2

Start / End Page

178 / 181

Location

United States

Related Subject Headings

  • Stevens-Johnson Syndrome
  • Phenytoin
  • Middle Aged
  • Methylprednisolone
  • Male
  • Humans
  • Drug Hypersensitivity
  • Dermatology & Venereal Diseases
  • Chemical and Drug Induced Liver Injury
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sherertz, E. F., Jegasothy, B. V., & Lazarus, G. S. (1985). Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy". J Am Acad Dermatol, 12(1 Pt 2), 178–181. https://doi.org/10.1016/s0190-9622(85)80012-8
Sherertz, E. F., B. V. Jegasothy, and G. S. Lazarus. “Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy".J Am Acad Dermatol 12, no. 1 Pt 2 (January 1985): 178–81. https://doi.org/10.1016/s0190-9622(85)80012-8.
Sherertz, E. F., et al. “Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis. Report of a patient treated with corticosteroid "pulse therapy".J Am Acad Dermatol, vol. 12, no. 1 Pt 2, Jan. 1985, pp. 178–81. Pubmed, doi:10.1016/s0190-9622(85)80012-8.
Journal cover image

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

January 1985

Volume

12

Issue

1 Pt 2

Start / End Page

178 / 181

Location

United States

Related Subject Headings

  • Stevens-Johnson Syndrome
  • Phenytoin
  • Middle Aged
  • Methylprednisolone
  • Male
  • Humans
  • Drug Hypersensitivity
  • Dermatology & Venereal Diseases
  • Chemical and Drug Induced Liver Injury
  • 1103 Clinical Sciences