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Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population.

Publication ,  Journal Article
Fenwick, EK; Man, REK; Gan, ATL; Kumari, N; Wong, C; Aravindhan, A; Gupta, P; Wang, JJ; Mitchell, P; Wong, TY; Cheng, C-Y; Lamoureux, EL
Published in: Br J Ophthalmol
September 2019

BACKGROUND/AIMS: To assess the independent impact of diabetic retinopathy (DR) on three domains of vision-related quality of life (VRQoL) in a Chinese Singapore population. METHODS: The Singapore Chinese Eye Study (n=3353; 2009-2011) was a population-based, prospective, cross-sectional study conducted at the Singapore Eye Research Institute. The study population included 292 adults with diabetes, with and without DR. DR (better eye) was categorised as presence and absence of any DR; severity of DR (no vision-threatening DR (VTDR); severe non-proliferative DR (NPDR); PDR and/or clinically significant macular oedema and VTDR). Our main outcome was VRQoL which was measured using Rasch-calibrated scores from the 'Reading', 'Mobility' and 'Emotional' domains of the Impact of Vision Impairment questionnaire. The relationship between DR and VRQoL was assessed using multiple linear regression models. RESULTS: Of the 292 individuals (mean age 61.35 ± 9.66 years; 55.8% male), 201 (68.8%), 49 (16.8%), 20 (6.8%), 22 (7.5%) and 27 (9.2%) had no DR, minimal-mild NPDR, moderate-severe NPDR, PDR and VTDR, respectively. Any DR and VTDR were independently associated with 6% and 12% worse Reading scores and 7% and 18% poorer Emotional well-being, respectively, compared with those without DR. These associations persisted after separate adjustment for visual impairment and presenting visual acuity. No significant difference was found in the Mobility domain between persons with and without DR. CONCLUSIONS: We documented that DR, particularly VTDR, was independently associated with restrictions in Reading and Emotional well-being. Understanding factors underlying the detrimental DR-VRQoL relationship may optimise rehabilitation outcomes for individuals with DR.

Duke Scholars

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Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

September 2019

Volume

103

Issue

9

Start / End Page

1314 / 1319

Location

England

Related Subject Headings

  • Vision Disorders
  • Singapore
  • Risk Factors
  • Regression Analysis
  • Reading
  • Quality of Life
  • Prospective Studies
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
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Fenwick, E. K., Man, R. E. K., Gan, A. T. L., Kumari, N., Wong, C., Aravindhan, A., … Lamoureux, E. L. (2019). Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population. Br J Ophthalmol, 103(9), 1314–1319. https://doi.org/10.1136/bjophthalmol-2018-313082
Fenwick, Eva K., Ryan E. K. Man, Alfred Tau Liang Gan, Neelam Kumari, Charlene Wong, Amudha Aravindhan, Preeti Gupta, et al. “Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population.Br J Ophthalmol 103, no. 9 (September 2019): 1314–19. https://doi.org/10.1136/bjophthalmol-2018-313082.
Fenwick EK, Man REK, Gan ATL, Kumari N, Wong C, Aravindhan A, et al. Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population. Br J Ophthalmol. 2019 Sep;103(9):1314–9.
Fenwick, Eva K., et al. “Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population.Br J Ophthalmol, vol. 103, no. 9, Sept. 2019, pp. 1314–19. Pubmed, doi:10.1136/bjophthalmol-2018-313082.
Fenwick EK, Man REK, Gan ATL, Kumari N, Wong C, Aravindhan A, Gupta P, Wang JJ, Mitchell P, Wong TY, Cheng C-Y, Lamoureux EL. Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population. Br J Ophthalmol. 2019 Sep;103(9):1314–1319.

Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

September 2019

Volume

103

Issue

9

Start / End Page

1314 / 1319

Location

England

Related Subject Headings

  • Vision Disorders
  • Singapore
  • Risk Factors
  • Regression Analysis
  • Reading
  • Quality of Life
  • Prospective Studies
  • Ophthalmology & Optometry
  • Middle Aged
  • Male