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Hematopoietic Stem Cell Transplantation

Late complications of hematopoietic stem cell transplantation

Publication ,  Chapter
Kansu, E; Sullivan, KM
January 1, 2000

I. INTRODUCTION Stem cell transplantation of peripheral blood or bone marrow has evolved into an accepted treatment for a variety of life-threatening hematological, neoplastic, and immunological disorders. The numbers and types of transplants have increased as unrelated and mismatched related individuals are now used as alternative donors, as different sources of hematopoietic stem cells are employed, and as new disease indications are considered for transplantation (Kernan et al., 1993; Kurtzberg et al., 1996; Walters et al., 1996). As transplant outcomes improve with advances in supportive care, new treatment protocols are being developed to extend the application of stem cell transplantation to nonmalignant conditions such as sickle cell disease, thalassemia, and selected autoimmune disorders (Lucarelli et al., 1993; Sullivan and Furst, 1997). As shown in Fig. 1, there has been a steady increase in the number of transplant centers and an increasing number of longterm survivors (Armitage, 1994). Thousands of patients worldwide are currently alive more than 5 years following bone marrow transplantation and increasing attention is being directed to potential late complications (Sullivan et al., 1991).

Duke Scholars

ISBN

9780824702731

Publication Date

January 1, 2000

Start / End Page

413 / 433
 

Citation

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Kansu, E., & Sullivan, K. M. (2000). Late complications of hematopoietic stem cell transplantation. In Hematopoietic Stem Cell Transplantation (pp. 413–433).
Kansu, E., and K. M. Sullivan. “Late complications of hematopoietic stem cell transplantation.” In Hematopoietic Stem Cell Transplantation, 413–33, 2000.
Kansu E, Sullivan KM. Late complications of hematopoietic stem cell transplantation. In: Hematopoietic Stem Cell Transplantation. 2000. p. 413–33.
Kansu, E., and K. M. Sullivan. “Late complications of hematopoietic stem cell transplantation.” Hematopoietic Stem Cell Transplantation, 2000, pp. 413–33.
Kansu E, Sullivan KM. Late complications of hematopoietic stem cell transplantation. Hematopoietic Stem Cell Transplantation. 2000. p. 413–433.
Journal cover image

ISBN

9780824702731

Publication Date

January 1, 2000

Start / End Page

413 / 433