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Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists.

Publication ,  Journal Article
Ivascu, NS; Fitzgerald, M; Ghadimi, K; Patel, P; Evans, AS; Goeddel, LA; Shaefi, S; Klick, J; Johnson, A; Raiten, J; Horak, J; Gutsche, J
Published in: J Cardiothorac Vasc Anesth
February 2019

Patients undergoing cardiovascular surgery may be exposed to heparin before surgery, during cardiopulmonary bypass (CPB), or in the immediate postoperative period. For this reason, cardiovascular surgery patients are at increased risk for heparin-induced thrombocytopenia (HIT), occurring in 1 to 3% of patients. The diagnosis of HIT can be difficult, if based solely on the development of thrombocytopenia, because cardiac surgical patients have multiple reasons to be thrombocytopenic. Several clinical scoring systems have been developed to reduce unnecessary testing and better define the pretest probability of HIT, which we will review in detail with a diagnostic algorithm. In addition, we will cover the prevention and treatment HIT.

Duke Scholars

Published In

J Cardiothorac Vasc Anesth

DOI

EISSN

1532-8422

Publication Date

February 2019

Volume

33

Issue

2

Start / End Page

511 / 520

Location

United States

Related Subject Headings

  • Thromboembolism
  • Thrombocytopenia
  • Postoperative Complications
  • Humans
  • Heparin
  • Critical Care
  • Cardiopulmonary Bypass
  • Anticoagulants
  • Anesthesiology
  • Anesthesiologists
 

Citation

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Ivascu, N. S., Fitzgerald, M., Ghadimi, K., Patel, P., Evans, A. S., Goeddel, L. A., … Gutsche, J. (2019). Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists. J Cardiothorac Vasc Anesth, 33(2), 511–520. https://doi.org/10.1053/j.jvca.2018.10.035
Ivascu, Natalia S., Meghann Fitzgerald, Kamrouz Ghadimi, Prakash Patel, Adam S. Evans, Lee A. Goeddel, Shaz Shaefi, et al. “Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists.J Cardiothorac Vasc Anesth 33, no. 2 (February 2019): 511–20. https://doi.org/10.1053/j.jvca.2018.10.035.
Ivascu NS, Fitzgerald M, Ghadimi K, Patel P, Evans AS, Goeddel LA, et al. Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists. J Cardiothorac Vasc Anesth. 2019 Feb;33(2):511–20.
Ivascu, Natalia S., et al. “Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists.J Cardiothorac Vasc Anesth, vol. 33, no. 2, Feb. 2019, pp. 511–20. Pubmed, doi:10.1053/j.jvca.2018.10.035.
Ivascu NS, Fitzgerald M, Ghadimi K, Patel P, Evans AS, Goeddel LA, Shaefi S, Klick J, Johnson A, Raiten J, Horak J, Gutsche J. Heparin-Induced Thrombocytopenia: A Review for Cardiac Anesthesiologists and Intensivists. J Cardiothorac Vasc Anesth. 2019 Feb;33(2):511–520.
Journal cover image

Published In

J Cardiothorac Vasc Anesth

DOI

EISSN

1532-8422

Publication Date

February 2019

Volume

33

Issue

2

Start / End Page

511 / 520

Location

United States

Related Subject Headings

  • Thromboembolism
  • Thrombocytopenia
  • Postoperative Complications
  • Humans
  • Heparin
  • Critical Care
  • Cardiopulmonary Bypass
  • Anticoagulants
  • Anesthesiology
  • Anesthesiologists