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Parabens: Contact (Non)Allergen of the Year.

Publication ,  Journal Article
Fransway, AF; Fransway, PJ; Belsito, DV; Warshaw, EM; Sasseville, D; Fowler, JF; DeKoven, JG; Pratt, MD; Maibach, HI; Taylor, JS; Marks, JG ...
Published in: Dermatitis
December 18, 2018

Parabens have been widely used as preservatives in the cosmetics, food, and pharmaceutical industries for more than 70 years. Monitoring for paraben allergy closely followed with studies reporting paraben testing in standard screening fashion as early as 1940. The frequency of sensitivity to this widely used biocide has remained low and remarkably stable for many decades despite extensive use and progressive expansion of utilization worldwide. The authors select paraben mix as the (non)allergen of the year. Paraben reactions are quite uncommon and generally relevant. Parabens remain one of the least allergenic preservatives available. The unsubstantiated public perception of paraben safety has led to its replacement in many products with preservatives having far greater allergenic potential. This report reviews the well-established safety of parabens from an allergologic standpoint.

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Published In

Dermatitis

DOI

EISSN

2162-5220

Publication Date

December 18, 2018

Location

United States

Related Subject Headings

  • Preservatives, Pharmaceutical
  • Patch Tests
  • Parabens
  • Immunization
  • Humans
  • Food Preservatives
  • Dermatology & Venereal Diseases
  • Dermatitis, Allergic Contact
  • Cosmetics
  • 3204 Immunology
 

Citation

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Fransway, A. F., Fransway, P. J., Belsito, D. V., Warshaw, E. M., Sasseville, D., Fowler, J. F., … Reeder, M. J. (2018). Parabens: Contact (Non)Allergen of the Year. Dermatitis. https://doi.org/10.1097/DER.0000000000000429
Fransway, Anthony F., Paulina J. Fransway, Donald V. Belsito, Erin M. Warshaw, Denis Sasseville, Joseph F. Fowler, Joel G. DeKoven, et al. “Parabens: Contact (Non)Allergen of the Year.Dermatitis, December 18, 2018. https://doi.org/10.1097/DER.0000000000000429.
Fransway AF, Fransway PJ, Belsito DV, Warshaw EM, Sasseville D, Fowler JF, et al. Parabens: Contact (Non)Allergen of the Year. Dermatitis. 2018 Dec 18;
Fransway, Anthony F., et al. “Parabens: Contact (Non)Allergen of the Year.Dermatitis, Dec. 2018. Pubmed, doi:10.1097/DER.0000000000000429.
Fransway AF, Fransway PJ, Belsito DV, Warshaw EM, Sasseville D, Fowler JF, DeKoven JG, Pratt MD, Maibach HI, Taylor JS, Marks JG, Mathias CGT, DeLeo VA, Zirwas JM, Zug KA, Atwater AR, Silverberg J, Reeder MJ. Parabens: Contact (Non)Allergen of the Year. Dermatitis. 2018 Dec 18;

Published In

Dermatitis

DOI

EISSN

2162-5220

Publication Date

December 18, 2018

Location

United States

Related Subject Headings

  • Preservatives, Pharmaceutical
  • Patch Tests
  • Parabens
  • Immunization
  • Humans
  • Food Preservatives
  • Dermatology & Venereal Diseases
  • Dermatitis, Allergic Contact
  • Cosmetics
  • 3204 Immunology