
Manipulating the gut microbiome to decrease uremic toxins.
Publication
, Journal Article
Yacoub, R; Wyatt, CM
Published in: Kidney Int
March 2017
The uremic solute indoxyl sulfate has been associated with increased mortality and other adverse outcomes in patients with chronic kidney disease. In a recent study published in Cell Host & Microbe, Devlin et al. describe a novel approach to alter the production of indoxyl sulfate through manipulation of the gut microbiota. Although this approach is far from clinical application, it may allow investigators to determine the contribution of uremic solutes to disease pathogenesis.
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Published In
Kidney Int
DOI
EISSN
1523-1755
Publication Date
March 2017
Volume
91
Issue
3
Start / End Page
521 / 523
Location
United States
Related Subject Headings
- Urology & Nephrology
- Uremia
- Phenotype
- Mutation
- Indican
- Humans
- Genotype
- Gastrointestinal Tract
- Gastrointestinal Microbiome
- Bacteroides
Citation
APA
Chicago
ICMJE
MLA
NLM
Yacoub, R., & Wyatt, C. M. (2017). Manipulating the gut microbiome to decrease uremic toxins. Kidney Int, 91(3), 521–523. https://doi.org/10.1016/j.kint.2017.01.003
Yacoub, Rabi, and Christina M. Wyatt. “Manipulating the gut microbiome to decrease uremic toxins.” Kidney Int 91, no. 3 (March 2017): 521–23. https://doi.org/10.1016/j.kint.2017.01.003.
Yacoub R, Wyatt CM. Manipulating the gut microbiome to decrease uremic toxins. Kidney Int. 2017 Mar;91(3):521–3.
Yacoub, Rabi, and Christina M. Wyatt. “Manipulating the gut microbiome to decrease uremic toxins.” Kidney Int, vol. 91, no. 3, Mar. 2017, pp. 521–23. Pubmed, doi:10.1016/j.kint.2017.01.003.
Yacoub R, Wyatt CM. Manipulating the gut microbiome to decrease uremic toxins. Kidney Int. 2017 Mar;91(3):521–523.

Published In
Kidney Int
DOI
EISSN
1523-1755
Publication Date
March 2017
Volume
91
Issue
3
Start / End Page
521 / 523
Location
United States
Related Subject Headings
- Urology & Nephrology
- Uremia
- Phenotype
- Mutation
- Indican
- Humans
- Genotype
- Gastrointestinal Tract
- Gastrointestinal Microbiome
- Bacteroides