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Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region.

Publication ,  Journal Article
Atik, AF; Calabrese, E; Gramer, R; Adil, SM; Rahimpour, S; Pagadala, P; Johnson, GA; Lad, SP
Published in: Neuroimage
August 1, 2019

Human spinal white matter tract anatomy has been mapped using post mortem histological information with the help of molecular tracing studies in animal models. This study used 7 Tesla diffusion MR tractography on a human cadaver that was harvested 24 hours post mortem to evaluate cuneate fasciculus anatomy in cervical spinal cord. Based on this method, for the first time much more nuanced tractographic anatomy was used to investigate possible new routes for cuneate fasciculus in the posterior and lateral funiculus. Additionally, current molecular tracing studies were reviewed, and confirmatory data was presented along with our radiological results. Both studies confirm that upon entry to the spinal cord, upper cervical level tracts (C1-2-3) travel inside lateral funiculus and lower level tracts travel medially inside the posterior funiculus after entry at posterolateral sulcus which is different than traditional knowledge of having cuneate fasciculus tracts concentrated in the lateral part of posterior funiculus.

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Published In

Neuroimage

DOI

EISSN

1095-9572

Publication Date

August 1, 2019

Volume

196

Start / End Page

200 / 206

Location

United States

Related Subject Headings

  • White Matter
  • Neurology & Neurosurgery
  • Neural Pathways
  • Male
  • Image Processing, Computer-Assisted
  • Humans
  • Diffusion Tensor Imaging
  • Cervical Cord
  • Afferent Pathways
  • 42 Health sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Atik, A. F., Calabrese, E., Gramer, R., Adil, S. M., Rahimpour, S., Pagadala, P., … Lad, S. P. (2019). Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region. Neuroimage, 196, 200–206. https://doi.org/10.1016/j.neuroimage.2019.04.030
Atik, Ahmet Fatih, Evan Calabrese, Robert Gramer, Syed M. Adil, Shervin Rahimpour, Promila Pagadala, G Allan Johnson, and Shivanand P. Lad. “Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region.Neuroimage 196 (August 1, 2019): 200–206. https://doi.org/10.1016/j.neuroimage.2019.04.030.
Atik AF, Calabrese E, Gramer R, Adil SM, Rahimpour S, Pagadala P, et al. Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region. Neuroimage. 2019 Aug 1;196:200–6.
Atik, Ahmet Fatih, et al. “Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region.Neuroimage, vol. 196, Aug. 2019, pp. 200–06. Pubmed, doi:10.1016/j.neuroimage.2019.04.030.
Atik AF, Calabrese E, Gramer R, Adil SM, Rahimpour S, Pagadala P, Johnson GA, Lad SP. Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region. Neuroimage. 2019 Aug 1;196:200–206.
Journal cover image

Published In

Neuroimage

DOI

EISSN

1095-9572

Publication Date

August 1, 2019

Volume

196

Start / End Page

200 / 206

Location

United States

Related Subject Headings

  • White Matter
  • Neurology & Neurosurgery
  • Neural Pathways
  • Male
  • Image Processing, Computer-Assisted
  • Humans
  • Diffusion Tensor Imaging
  • Cervical Cord
  • Afferent Pathways
  • 42 Health sciences