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A statistical and biological response to an informatics appraisal of healthy aging gene signatures.

Publication ,  Journal Article
Timmons, JA; Gallagher, IJ; Sood, S; Phillips, B; Crossland, H; Howard, R; Kraus, WE; Atherton, PJ
Published in: Genome Biol
August 2, 2019

Jacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below.

Duke Scholars

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Published In

Genome Biol

DOI

EISSN

1474-760X

Publication Date

August 2, 2019

Volume

20

Issue

1

Start / End Page

152

Location

England

Related Subject Headings

  • RNA
  • Humans
  • Healthy Aging
  • Health Status
  • Cognition
  • Bioinformatics
  • Alzheimer Disease
  • 08 Information and Computing Sciences
  • 06 Biological Sciences
  • 05 Environmental Sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Timmons, J. A., Gallagher, I. J., Sood, S., Phillips, B., Crossland, H., Howard, R., … Atherton, P. J. (2019). A statistical and biological response to an informatics appraisal of healthy aging gene signatures. Genome Biol, 20(1), 152. https://doi.org/10.1186/s13059-019-1734-z
Timmons, James A., Iain J. Gallagher, Sanjana Sood, Bethan Phillips, Hannah Crossland, Robert Howard, William E. Kraus, and Philip J. Atherton. “A statistical and biological response to an informatics appraisal of healthy aging gene signatures.Genome Biol 20, no. 1 (August 2, 2019): 152. https://doi.org/10.1186/s13059-019-1734-z.
Timmons JA, Gallagher IJ, Sood S, Phillips B, Crossland H, Howard R, et al. A statistical and biological response to an informatics appraisal of healthy aging gene signatures. Genome Biol. 2019 Aug 2;20(1):152.
Timmons, James A., et al. “A statistical and biological response to an informatics appraisal of healthy aging gene signatures.Genome Biol, vol. 20, no. 1, Aug. 2019, p. 152. Pubmed, doi:10.1186/s13059-019-1734-z.
Timmons JA, Gallagher IJ, Sood S, Phillips B, Crossland H, Howard R, Kraus WE, Atherton PJ. A statistical and biological response to an informatics appraisal of healthy aging gene signatures. Genome Biol. 2019 Aug 2;20(1):152.

Published In

Genome Biol

DOI

EISSN

1474-760X

Publication Date

August 2, 2019

Volume

20

Issue

1

Start / End Page

152

Location

England

Related Subject Headings

  • RNA
  • Humans
  • Healthy Aging
  • Health Status
  • Cognition
  • Bioinformatics
  • Alzheimer Disease
  • 08 Information and Computing Sciences
  • 06 Biological Sciences
  • 05 Environmental Sciences