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Corneal crosslinking: Current protocols and clinical approach.

Publication ,  Journal Article
Beckman, KA; Gupta, PK; Farid, M; Berdahl, JP; Yeu, E; Ayres, B; Chan, CC; Gomes, JAP; Holland, EJ; Kim, T; Starr, CE; Mah, FS ...
Published in: J Cataract Refract Surg
November 2019

Members of the ASCRS Cornea Clinical Committee performed a review of the current literature on the corneal crosslinking (CXL) procedure for treating corneal ectasia. The members explored the data on the techniques currently in use and under investigation, including their advantages, safety profiles, risks, and cost analyses, compared with data on corneal transplantation. They concluded that CXL limits the progression of keratoconus, thus reducing the need for transplantation. They also found that compared with permitting the disease to progress naturally, CXL techniques carry significant and long-term cost and safety benefits, primarily by reducing the need for corneal transplantation. Studies of various CXL techniques (eg, epithelium-on treatment, changes in ultraviolet light parameters, riboflavin composition) continue with the ultimate goal of improving the procedure's safety and efficacy.

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Published In

J Cataract Refract Surg

DOI

EISSN

1873-4502

Publication Date

November 2019

Volume

45

Issue

11

Start / End Page

1670 / 1679

Location

United States

Related Subject Headings

  • Ultraviolet Rays
  • Riboflavin
  • Photosensitizing Agents
  • Photochemotherapy
  • Ophthalmology & Optometry
  • Keratoconus
  • Humans
  • Cross-Linking Reagents
  • Corneal Stroma
  • Collagen
 

Citation

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Beckman, K. A., Gupta, P. K., Farid, M., Berdahl, J. P., Yeu, E., Ayres, B., … ASCRS Cornea Clinical Committee, . (2019). Corneal crosslinking: Current protocols and clinical approach. J Cataract Refract Surg, 45(11), 1670–1679. https://doi.org/10.1016/j.jcrs.2019.06.027
Beckman, Kenneth A., Preeya K. Gupta, Marjan Farid, John P. Berdahl, Elizabeth Yeu, Brandon Ayres, Clara C. Chan, et al. “Corneal crosslinking: Current protocols and clinical approach.J Cataract Refract Surg 45, no. 11 (November 2019): 1670–79. https://doi.org/10.1016/j.jcrs.2019.06.027.
Beckman KA, Gupta PK, Farid M, Berdahl JP, Yeu E, Ayres B, et al. Corneal crosslinking: Current protocols and clinical approach. J Cataract Refract Surg. 2019 Nov;45(11):1670–9.
Beckman, Kenneth A., et al. “Corneal crosslinking: Current protocols and clinical approach.J Cataract Refract Surg, vol. 45, no. 11, Nov. 2019, pp. 1670–79. Pubmed, doi:10.1016/j.jcrs.2019.06.027.
Beckman KA, Gupta PK, Farid M, Berdahl JP, Yeu E, Ayres B, Chan CC, Gomes JAP, Holland EJ, Kim T, Starr CE, Mah FS, ASCRS Cornea Clinical Committee. Corneal crosslinking: Current protocols and clinical approach. J Cataract Refract Surg. 2019 Nov;45(11):1670–1679.
Journal cover image

Published In

J Cataract Refract Surg

DOI

EISSN

1873-4502

Publication Date

November 2019

Volume

45

Issue

11

Start / End Page

1670 / 1679

Location

United States

Related Subject Headings

  • Ultraviolet Rays
  • Riboflavin
  • Photosensitizing Agents
  • Photochemotherapy
  • Ophthalmology & Optometry
  • Keratoconus
  • Humans
  • Cross-Linking Reagents
  • Corneal Stroma
  • Collagen