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Trichoblastic carcinosarcoma: A case report and literature review.

Publication ,  Journal Article
Underwood, CIM; Mansoori, P; Selim, AM; Al-Rohil, RN
Published in: J Cutan Pathol
April 2020

Trichoblastic carcinosarcoma is a rare biphasic adnexal neoplasm. This case report chronicals the eighth occurrence of this tumor published in the English literature and provides a review of the prior publications. Clinically, this tumor presents as an isolated, rapidly growing lesion in elderly patients and is usually cured by complete surgical excision, with no evidence of recurrence or metastasis at follow-up (7/8 cases). Histopathologically, trichoblastic carcinosarcoma is dermal-based, with an epithelial component of basal cells and a mesenchymal component of spindle cells, both of which display malignant features. In addition to a morphologic description of trichoblastic carcinosarcoma, a discussion of the differential diagnoses, including other biphasic neoplasms, is also included. The small number of cases of trichoblastic carcinosarcoma is most likely secondary to under-recognition and underreporting and a larger case volume is needed to more accurately assess the clinical course and treatment strategies.

Duke Scholars

Published In

J Cutan Pathol

DOI

EISSN

1600-0560

Publication Date

April 2020

Volume

47

Issue

4

Start / End Page

409 / 413

Location

United States

Related Subject Headings

  • Skin Neoplasms
  • Male
  • Humans
  • Head and Neck Neoplasms
  • Dermis
  • Dermatology & Venereal Diseases
  • Carcinosarcoma
  • Aged
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
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ICMJE
MLA
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Underwood, C. I. M., Mansoori, P., Selim, A. M., & Al-Rohil, R. N. (2020). Trichoblastic carcinosarcoma: A case report and literature review. J Cutan Pathol, 47(4), 409–413. https://doi.org/10.1111/cup.13614
Underwood, Caroline I. M., Parisa Mansoori, Angelica M. Selim, and Rami N. Al-Rohil. “Trichoblastic carcinosarcoma: A case report and literature review.J Cutan Pathol 47, no. 4 (April 2020): 409–13. https://doi.org/10.1111/cup.13614.
Underwood CIM, Mansoori P, Selim AM, Al-Rohil RN. Trichoblastic carcinosarcoma: A case report and literature review. J Cutan Pathol. 2020 Apr;47(4):409–13.
Underwood, Caroline I. M., et al. “Trichoblastic carcinosarcoma: A case report and literature review.J Cutan Pathol, vol. 47, no. 4, Apr. 2020, pp. 409–13. Pubmed, doi:10.1111/cup.13614.
Underwood CIM, Mansoori P, Selim AM, Al-Rohil RN. Trichoblastic carcinosarcoma: A case report and literature review. J Cutan Pathol. 2020 Apr;47(4):409–413.
Journal cover image

Published In

J Cutan Pathol

DOI

EISSN

1600-0560

Publication Date

April 2020

Volume

47

Issue

4

Start / End Page

409 / 413

Location

United States

Related Subject Headings

  • Skin Neoplasms
  • Male
  • Humans
  • Head and Neck Neoplasms
  • Dermis
  • Dermatology & Venereal Diseases
  • Carcinosarcoma
  • Aged
  • 3202 Clinical sciences
  • 1103 Clinical Sciences