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Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease.

Publication ,  Journal Article
Klein, LJ; Pendse, AA; Mittenzwei, R; Noel, R
Published in: J Adolesc Health
March 2020

Abdominal pain is a common symptom in Crohn's disease, presumably associated with mucosal inflammation and/or luminal stenosis. However, pain is not specific to Crohn's disease, and other etiologies should be considered, particularly gynecologic pathology in an adolescent female. We present an unusual case of endometrial tissue found in the colonic polyp of an adolescent with known Crohn's disease and abdominal pain. Histologic analysis differentiated endometriosis from active inflammation secondary to Crohn's disease. Endometriosis and Crohn's disease are both classified as chronic inflammatory disorders. It remains unclear whether overlapping etiological factors exist for the two disorders. There is a paucity of data on comanagement of endometriosis and inflammatory bowel disease, especially in adolescents. Given the finding of endometriosis in the colonic polyp was unanticipated, this case also reinforces the merits of endoscopic staging of disease whenever significant changes in therapy are considered.

Duke Scholars

Published In

J Adolesc Health

DOI

EISSN

1879-1972

Publication Date

March 2020

Volume

66

Issue

3

Start / End Page

375 / 377

Location

United States

Related Subject Headings

  • Public Health
  • Inflammatory Bowel Diseases
  • Humans
  • Female
  • Endometriosis
  • Diagnosis, Differential
  • Crohn Disease
  • Colonoscopy
  • Colonic Polyps
  • Biopsy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Klein, L. J., Pendse, A. A., Mittenzwei, R., & Noel, R. (2020). Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease. J Adolesc Health, 66(3), 375–377. https://doi.org/10.1016/j.jadohealth.2019.09.018
Klein, Lauren J., Avani A. Pendse, Rhonda Mittenzwei, and Richard Noel. “Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease.J Adolesc Health 66, no. 3 (March 2020): 375–77. https://doi.org/10.1016/j.jadohealth.2019.09.018.
Klein LJ, Pendse AA, Mittenzwei R, Noel R. Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease. J Adolesc Health. 2020 Mar;66(3):375–7.
Klein, Lauren J., et al. “Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease.J Adolesc Health, vol. 66, no. 3, Mar. 2020, pp. 375–77. Pubmed, doi:10.1016/j.jadohealth.2019.09.018.
Klein LJ, Pendse AA, Mittenzwei R, Noel R. Defying Occam's Razor: Colonic Luminal Endometriosis in an Adolescent With Crohn's Disease. J Adolesc Health. 2020 Mar;66(3):375–377.
Journal cover image

Published In

J Adolesc Health

DOI

EISSN

1879-1972

Publication Date

March 2020

Volume

66

Issue

3

Start / End Page

375 / 377

Location

United States

Related Subject Headings

  • Public Health
  • Inflammatory Bowel Diseases
  • Humans
  • Female
  • Endometriosis
  • Diagnosis, Differential
  • Crohn Disease
  • Colonoscopy
  • Colonic Polyps
  • Biopsy