Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis.
Publication
, Journal Article
Yang, W-H; Chi, J-T
Published in: Mol Cell Oncol
2020
Ferroptosis is a novel form of programmed cell death. We found that the ferroptosis sensitivity in renal and ovarian cancers are regulated by cell density through TAZ-EMP1-NOX4 and TAZ-ANGPTL4-NOX2 pathway, respectively. These findings reveal TAZ as a novel genetic determinant of ferroptosis. Triggering ferroptosis may have therapeutic potential for TAZ-activated tumors.
Duke Scholars
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Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
2020
Volume
7
Issue
1
Start / End Page
1699375
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics
Citation
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Chicago
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MLA
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Yang, W.-H., & Chi, J.-T. (2020). Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis. Mol Cell Oncol, 7(1), 1699375. https://doi.org/10.1080/23723556.2019.1699375
Yang, Wen-Hsuan, and Jen-Tsan Chi. “Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis.” Mol Cell Oncol 7, no. 1 (2020): 1699375. https://doi.org/10.1080/23723556.2019.1699375.
Yang W-H, Chi J-T. Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis. Mol Cell Oncol. 2020;7(1):1699375.
Yang, Wen-Hsuan, and Jen-Tsan Chi. “Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis.” Mol Cell Oncol, vol. 7, no. 1, 2020, p. 1699375. Pubmed, doi:10.1080/23723556.2019.1699375.
Yang W-H, Chi J-T. Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis. Mol Cell Oncol. 2020;7(1):1699375.
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
2020
Volume
7
Issue
1
Start / End Page
1699375
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics