Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Association between endometriosis and gynecological cancers: a critical review of the literature.

Publication ,  Journal Article
Kalaitzopoulos, DR; Mitsopoulou, A; Iliopoulou, SM; Daniilidis, A; Samartzis, EP; Economopoulos, KP
Published in: Archives of gynecology and obstetrics
February 2020

Endometriosis is one of the most common benign gynecological diseases with an occurrence approximately 10% in reproductive age. Endometriosis has been proposed as a possible precursor of certain ovarian carcinomas such as clear cell and endometrioid ovarian carcinomas. In addition to this pathogenic link, the association with other gynecological tumors and breast cancer has been studied on an epidemiological basis in several studies.The aim of this review was to critically present the recent published evidence on the association of endometriosis with gynecological cancer, and with a special emphasis on ovarian cancer.A search for eligible studies was conducted in three electronic databases, MEDLINE, EMBASE and CINAHL, for original research in humans published in any language.The present review includes studies examining the association between endometriosis and different types of gynecological cancer (i.e., 25 studies on ovarian cancer, 8 studies on breast cancer, 8 studies on endometrial cancer and 2 studies on cervical cancer).The present literature supports the pre-existing evidence suggesting an association between ovarian cancer and endometriosis and specifically its two histologic subtypes (endometrioid and ovarian clear cell cancer). The most recent population-based epidemiological studies cannot provide a clear association between endometriosis and endometrial, cervical or breast cancer.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Archives of gynecology and obstetrics

DOI

EISSN

1432-0711

ISSN

0932-0067

Publication Date

February 2020

Volume

301

Issue

2

Start / End Page

355 / 367

Related Subject Headings

  • Uterine Cervical Neoplasms
  • Ovarian Neoplasms
  • Obstetrics & Reproductive Medicine
  • Middle Aged
  • Humans
  • Gynecology
  • Genital Neoplasms, Female
  • Female
  • Endometrium
  • Endometriosis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kalaitzopoulos, D. R., Mitsopoulou, A., Iliopoulou, S. M., Daniilidis, A., Samartzis, E. P., & Economopoulos, K. P. (2020). Association between endometriosis and gynecological cancers: a critical review of the literature. Archives of Gynecology and Obstetrics, 301(2), 355–367. https://doi.org/10.1007/s00404-020-05445-1
Kalaitzopoulos, Dimitrios Rafail, Angeliki Mitsopoulou, Sotiria Maria Iliopoulou, Angelos Daniilidis, Eleftherios P. Samartzis, and Konstantinos P. Economopoulos. “Association between endometriosis and gynecological cancers: a critical review of the literature.Archives of Gynecology and Obstetrics 301, no. 2 (February 2020): 355–67. https://doi.org/10.1007/s00404-020-05445-1.
Kalaitzopoulos DR, Mitsopoulou A, Iliopoulou SM, Daniilidis A, Samartzis EP, Economopoulos KP. Association between endometriosis and gynecological cancers: a critical review of the literature. Archives of gynecology and obstetrics. 2020 Feb;301(2):355–67.
Kalaitzopoulos, Dimitrios Rafail, et al. “Association between endometriosis and gynecological cancers: a critical review of the literature.Archives of Gynecology and Obstetrics, vol. 301, no. 2, Feb. 2020, pp. 355–67. Epmc, doi:10.1007/s00404-020-05445-1.
Kalaitzopoulos DR, Mitsopoulou A, Iliopoulou SM, Daniilidis A, Samartzis EP, Economopoulos KP. Association between endometriosis and gynecological cancers: a critical review of the literature. Archives of gynecology and obstetrics. 2020 Feb;301(2):355–367.
Journal cover image

Published In

Archives of gynecology and obstetrics

DOI

EISSN

1432-0711

ISSN

0932-0067

Publication Date

February 2020

Volume

301

Issue

2

Start / End Page

355 / 367

Related Subject Headings

  • Uterine Cervical Neoplasms
  • Ovarian Neoplasms
  • Obstetrics & Reproductive Medicine
  • Middle Aged
  • Humans
  • Gynecology
  • Genital Neoplasms, Female
  • Female
  • Endometrium
  • Endometriosis