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Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States.

Publication ,  Journal Article
Osazuwa-Peters, N; Massa, ST; Christopher, KM; Walker, RJ; Varvares, MA
Published in: J Cancer Res Clin Oncol
February 2016

PURPOSE: To investigate the effect of race and sex on long-term survival of oral and oropharyngeal cancer. METHODS: The Surveillance, Epidemiology and End Results database was queried for adult oral and oropharyngeal cancer patients with at least 25-year follow-up. Kaplan-Meier survival curves and cox proportional hazards model were used to identify differences. RESULTS: Of the 22,162 patients identified, 70.3% were males. Only 8.9% were alive at 25 years post-diagnosis. Black males show the poorest overall and disease-specific survival rates (p < 0.001). After controlling for covariates, Blacks had a 40% higher hazard of mortality compared with Whites (HR 1.40, 95% CI 1.35-1.46), while females had a 9% reduction in mortality risk (HR 0.91, 95% CI 0.88-0.94). CONCLUSIONS: Overall and disease-specific survival is poor for oral and oropharyngeal cancer patients, and Black men fare worst. This illustrates the need for long-term cancer survival plans incorporating disparity effects in overall cancer outcomes.

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Published In

J Cancer Res Clin Oncol

DOI

EISSN

1432-1335

Publication Date

February 2016

Volume

142

Issue

2

Start / End Page

521 / 528

Location

Germany

Related Subject Headings

  • White People
  • United States
  • Survivors
  • Sex Factors
  • SEER Program
  • Oropharyngeal Neoplasms
  • Oncology & Carcinogenesis
  • Multivariate Analysis
  • Mouth Neoplasms
  • Middle Aged
 

Citation

APA
Chicago
ICMJE
MLA
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Osazuwa-Peters, N., Massa, S. T., Christopher, K. M., Walker, R. J., & Varvares, M. A. (2016). Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States. J Cancer Res Clin Oncol, 142(2), 521–528. https://doi.org/10.1007/s00432-015-2061-8
Osazuwa-Peters, Nosayaba, Sean T. Massa, Kara M. Christopher, Ronald J. Walker, and Mark A. Varvares. “Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States.J Cancer Res Clin Oncol 142, no. 2 (February 2016): 521–28. https://doi.org/10.1007/s00432-015-2061-8.
Osazuwa-Peters N, Massa ST, Christopher KM, Walker RJ, Varvares MA. Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States. J Cancer Res Clin Oncol. 2016 Feb;142(2):521–8.
Osazuwa-Peters, Nosayaba, et al. “Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States.J Cancer Res Clin Oncol, vol. 142, no. 2, Feb. 2016, pp. 521–28. Pubmed, doi:10.1007/s00432-015-2061-8.
Osazuwa-Peters N, Massa ST, Christopher KM, Walker RJ, Varvares MA. Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States. J Cancer Res Clin Oncol. 2016 Feb;142(2):521–528.

Published In

J Cancer Res Clin Oncol

DOI

EISSN

1432-1335

Publication Date

February 2016

Volume

142

Issue

2

Start / End Page

521 / 528

Location

Germany

Related Subject Headings

  • White People
  • United States
  • Survivors
  • Sex Factors
  • SEER Program
  • Oropharyngeal Neoplasms
  • Oncology & Carcinogenesis
  • Multivariate Analysis
  • Mouth Neoplasms
  • Middle Aged