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Intravenous Migraine Treatment in Children and Adolescents.

Publication ,  Journal Article
Werner, K; Qaiser, S; Kabbouche, M; Murphy, B; Maconochie, I; Hershey, AD
Published in: Curr Pain Headache Rep
July 8, 2020

PURPOSE OF REVIEW: Pediatric migraine is a common, chronic, and disabling neurological disorder in children and adolescents. Outpatient management is not always effective, and intravenous migraine management may be necessary for headache treatment in the pediatric emergency department. Most current treatment is based on retrospective evidence and there is a lack of well-designed randomized double-blinded controlled pediatric studies. Intravenous drug treatment agents including intravenous fluids, prochlorperazine, diphenhydramine, metoclopramide, dexamethasone, magnesium, valproate and propofol, and dihydroergotamine are reviewed in this paper. RECENT FINDINGS: Nineteen studies were reviewed including one prospective randomized double-blind; one single-blinded randomized; one prospective; and one open-label, randomized clinical trial. Most studies were retrospective and the quality of the studies was limited. No definite conclusions can be drawn from the studies, but appropriate prospective trials between major pediatric headache institutions will move pediatric intravenous migraine management forward.

Duke Scholars

Published In

Curr Pain Headache Rep

DOI

EISSN

1534-3081

Publication Date

July 8, 2020

Volume

24

Issue

8

Start / End Page

45

Location

United States

Related Subject Headings

  • Vasoconstrictor Agents
  • Valproic Acid
  • Propofol
  • Prochlorperazine
  • Neurology & Neurosurgery
  • Migraine Disorders
  • Magnesium
  • Lidocaine
  • Ketorolac
  • Hypnotics and Sedatives
 

Citation

APA
Chicago
ICMJE
MLA
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Werner, K., Qaiser, S., Kabbouche, M., Murphy, B., Maconochie, I., & Hershey, A. D. (2020). Intravenous Migraine Treatment in Children and Adolescents. Curr Pain Headache Rep, 24(8), 45. https://doi.org/10.1007/s11916-020-00867-7
Werner, Klaus, Sharoon Qaiser, Marielle Kabbouche, Beverly Murphy, Ian Maconochie, and Andrew D. Hershey. “Intravenous Migraine Treatment in Children and Adolescents.Curr Pain Headache Rep 24, no. 8 (July 8, 2020): 45. https://doi.org/10.1007/s11916-020-00867-7.
Werner K, Qaiser S, Kabbouche M, Murphy B, Maconochie I, Hershey AD. Intravenous Migraine Treatment in Children and Adolescents. Curr Pain Headache Rep. 2020 Jul 8;24(8):45.
Werner, Klaus, et al. “Intravenous Migraine Treatment in Children and Adolescents.Curr Pain Headache Rep, vol. 24, no. 8, July 2020, p. 45. Pubmed, doi:10.1007/s11916-020-00867-7.
Werner K, Qaiser S, Kabbouche M, Murphy B, Maconochie I, Hershey AD. Intravenous Migraine Treatment in Children and Adolescents. Curr Pain Headache Rep. 2020 Jul 8;24(8):45.
Journal cover image

Published In

Curr Pain Headache Rep

DOI

EISSN

1534-3081

Publication Date

July 8, 2020

Volume

24

Issue

8

Start / End Page

45

Location

United States

Related Subject Headings

  • Vasoconstrictor Agents
  • Valproic Acid
  • Propofol
  • Prochlorperazine
  • Neurology & Neurosurgery
  • Migraine Disorders
  • Magnesium
  • Lidocaine
  • Ketorolac
  • Hypnotics and Sedatives