Racial Disparity in Response to Prostate Cancer Systemic Therapies.
Publication
, Journal Article
Bitting, RL; Goodman, M; George, DJ
Published in: Curr Oncol Rep
July 23, 2020
PURPOSE OF REVIEW: In this review, we aim to describe racial differences in response to treatment for metastatic castration-resistant prostate cancer (mCRPC). RECENT FINDINGS: Recent data suggests that, despite higher risk features, African Americans may respond better than Caucasians to systemic therapies for advanced prostate cancer. This improved response is not limited to one class of drugs but can be seen with androgen-pathway directed therapies, chemotherapy, bone-targeted therapy, and immunotherapy. The mechanisms for this are being further explored. African Americans may respond better to mCRPC treatments but validation in prospective clinical trials is needed.
Duke Scholars
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Published In
Curr Oncol Rep
DOI
EISSN
1534-6269
Publication Date
July 23, 2020
Volume
22
Issue
9
Start / End Page
96
Location
United States
Related Subject Headings
- White People
- Prostatic Neoplasms
- Oncology & Carcinogenesis
- Male
- Immunotherapy
- Humans
- Healthcare Disparities
- Black or African American
- Androgen Antagonists
- 3211 Oncology and carcinogenesis
Citation
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Chicago
ICMJE
MLA
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Bitting, R. L., Goodman, M., & George, D. J. (2020). Racial Disparity in Response to Prostate Cancer Systemic Therapies. Curr Oncol Rep, 22(9), 96. https://doi.org/10.1007/s11912-020-00966-z
Bitting, Rhonda L., Michael Goodman, and Daniel J. George. “Racial Disparity in Response to Prostate Cancer Systemic Therapies.” Curr Oncol Rep 22, no. 9 (July 23, 2020): 96. https://doi.org/10.1007/s11912-020-00966-z.
Bitting RL, Goodman M, George DJ. Racial Disparity in Response to Prostate Cancer Systemic Therapies. Curr Oncol Rep. 2020 Jul 23;22(9):96.
Bitting, Rhonda L., et al. “Racial Disparity in Response to Prostate Cancer Systemic Therapies.” Curr Oncol Rep, vol. 22, no. 9, July 2020, p. 96. Pubmed, doi:10.1007/s11912-020-00966-z.
Bitting RL, Goodman M, George DJ. Racial Disparity in Response to Prostate Cancer Systemic Therapies. Curr Oncol Rep. 2020 Jul 23;22(9):96.
Published In
Curr Oncol Rep
DOI
EISSN
1534-6269
Publication Date
July 23, 2020
Volume
22
Issue
9
Start / End Page
96
Location
United States
Related Subject Headings
- White People
- Prostatic Neoplasms
- Oncology & Carcinogenesis
- Male
- Immunotherapy
- Humans
- Healthcare Disparities
- Black or African American
- Androgen Antagonists
- 3211 Oncology and carcinogenesis