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Real-world opioid prescribing after cataract surgery among patients who received intracameral phenylephrine and ketorolac 1.0%/0.3.

Publication ,  Journal Article
Jackson, K; Wisely, CE; Davis, BM; Griffin, B; Kim, T
Published in: Curr Med Res Opin
December 2020

OBJECTIVE: To examine opioid prescribing following cataract surgery among patients who did or did not receive Omidria (phenylephrine and ketorolac intraocular solution 1.0%/0.3%) referred to as "P/K". METHODS: The retrospective study compared adults over 65 without recent opioid use in the MarketScan databases who had a cataract-related surgical procedure between 1 January 2015 and 31 July 2019. Opioid prescription fills in the initial 2 and 7 days following surgery were compared between patients who did or did not receive P/K during surgery. RESULTS: We identified 218,672 older adults with cataract-related surgical procedures, of whom 5145 received P/K during surgery. Within 2 days of surgery, 0.50% of P/K patients and 0.68% of non-P/K patients received at least one opioid prescription. Pill counts in the first prescription post-surgery were lower for patients who received P/K than those who did not receive P/K (20 vs 45 respectively, p = .015). Findings were similar when a 7 day window was used. The reduction in opioids prescribed to patients who received P/K occurred despite the P/K-treated patients having a significantly higher incidence of preoperative comorbidities or risk factors for surgical complexity than patients who did not receive P/K (46.6% vs 31.3%, p < .001). CONCLUSIONS: Patients without recent opioid use who received P/K during cataract surgery, despite greater incidence of preoperative comorbidities and higher risk for surgical complexity, were prescribed fewer opioid pills following surgery than patients who did not receive P/K.

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Published In

Curr Med Res Opin

DOI

EISSN

1473-4877

Publication Date

December 2020

Volume

36

Issue

12

Start / End Page

2047 / 2052

Location

England

Related Subject Headings

  • United States
  • Retrospective Studies
  • Prescriptions
  • Practice Patterns, Physicians'
  • Phenylephrine
  • Pain, Postoperative
  • Medicare
  • Male
  • Ketorolac
  • Humans
 

Citation

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ICMJE
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Jackson, K., Wisely, C. E., Davis, B. M., Griffin, B., & Kim, T. (2020). Real-world opioid prescribing after cataract surgery among patients who received intracameral phenylephrine and ketorolac 1.0%/0.3. Curr Med Res Opin, 36(12), 2047–2052. https://doi.org/10.1080/03007995.2020.1834373
Jackson, Kevin, C Ellis Wisely, Brian M. Davis, Brian Griffin, and Terry Kim. “Real-world opioid prescribing after cataract surgery among patients who received intracameral phenylephrine and ketorolac 1.0%/0.3.Curr Med Res Opin 36, no. 12 (December 2020): 2047–52. https://doi.org/10.1080/03007995.2020.1834373.
Jackson K, Wisely CE, Davis BM, Griffin B, Kim T. Real-world opioid prescribing after cataract surgery among patients who received intracameral phenylephrine and ketorolac 1.0%/0.3. Curr Med Res Opin. 2020 Dec;36(12):2047–52.
Jackson, Kevin, et al. “Real-world opioid prescribing after cataract surgery among patients who received intracameral phenylephrine and ketorolac 1.0%/0.3.Curr Med Res Opin, vol. 36, no. 12, Dec. 2020, pp. 2047–52. Pubmed, doi:10.1080/03007995.2020.1834373.
Jackson K, Wisely CE, Davis BM, Griffin B, Kim T. Real-world opioid prescribing after cataract surgery among patients who received intracameral phenylephrine and ketorolac 1.0%/0.3. Curr Med Res Opin. 2020 Dec;36(12):2047–2052.

Published In

Curr Med Res Opin

DOI

EISSN

1473-4877

Publication Date

December 2020

Volume

36

Issue

12

Start / End Page

2047 / 2052

Location

England

Related Subject Headings

  • United States
  • Retrospective Studies
  • Prescriptions
  • Practice Patterns, Physicians'
  • Phenylephrine
  • Pain, Postoperative
  • Medicare
  • Male
  • Ketorolac
  • Humans