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Masses of the Lacrimal Gland: Evaluation and Treatment

Publication ,  Journal Article
Kim, JS; Liss, J
Published in: Journal of Neurological Surgery, Part B: Skull Base
February 1, 2021

Lacrimal gland lesions account for approximately 9 to 10% of all biopsied orbital masses. Potential causes include nongranulomatous and granulomatous inflammation, autoimmune disease, lymphoproliferative disorders, benign epithelial proliferation, malignant neoplasia, and metastatic disease. Inflammatory lesions and lymphoproliferative disorders are the most common and may be unilateral or bilateral; they may also be localized to the orbit or associated with systemic disease. Both benign and malignant epithelial lacrimal gland masses tend to be unilateral and involve the orbital lobe, but a more rapid onset of symptoms and periorbital pain strongly suggest malignant disease. On orbital imaging, both inflammatory and lymphoproliferative lesions conform to the globe and surrounding structures, without changes in adjacent bone, whereas epithelial lacrimal gland masses often show scalloping of the lacrimal gland fossa. Malignant epithelial lacrimal gland tumors can also have radiographic evidence of bony invasion and destruction. Masses of the lacrimal gland may be due to a broad range of pathologies, and a good working knowledge of common clinical characteristics and radiographic imaging findings is essential for diagnosis and treatment. All patients with inflammatory, lymphoproliferative, and epithelial neoplastic lesions involving the lacrimal gland require long-term surveillance for disease recurrence and progression.

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Published In

Journal of Neurological Surgery, Part B: Skull Base

DOI

EISSN

2193-6331

ISSN

2193-634X

Publication Date

February 1, 2021

Volume

82

Issue

1

Start / End Page

100 / 106
 

Citation

APA
Chicago
ICMJE
MLA
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Kim, J. S., & Liss, J. (2021). Masses of the Lacrimal Gland: Evaluation and Treatment. Journal of Neurological Surgery, Part B: Skull Base, 82(1), 100–106. https://doi.org/10.1055/s-0040-1722700
Kim, J. S., and J. Liss. “Masses of the Lacrimal Gland: Evaluation and Treatment.” Journal of Neurological Surgery, Part B: Skull Base 82, no. 1 (February 1, 2021): 100–106. https://doi.org/10.1055/s-0040-1722700.
Kim JS, Liss J. Masses of the Lacrimal Gland: Evaluation and Treatment. Journal of Neurological Surgery, Part B: Skull Base. 2021 Feb 1;82(1):100–6.
Kim, J. S., and J. Liss. “Masses of the Lacrimal Gland: Evaluation and Treatment.” Journal of Neurological Surgery, Part B: Skull Base, vol. 82, no. 1, Feb. 2021, pp. 100–06. Scopus, doi:10.1055/s-0040-1722700.
Kim JS, Liss J. Masses of the Lacrimal Gland: Evaluation and Treatment. Journal of Neurological Surgery, Part B: Skull Base. 2021 Feb 1;82(1):100–106.
Journal cover image

Published In

Journal of Neurological Surgery, Part B: Skull Base

DOI

EISSN

2193-6331

ISSN

2193-634X

Publication Date

February 1, 2021

Volume

82

Issue

1

Start / End Page

100 / 106