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Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging.

Publication ,  Journal Article
Van Orden, K; Santos, J; Stanfield, B; Frost, LS; Ruditsky, A; Foster, A; Brahmbhatt, TS; Burke, PA; Fernandez-Moure, J; Haines, K; Agarwal, S ...
Published in: Eur J Trauma Emerg Surg
June 2022

BACKGROUND: The management of complicated ventral hernias (CVH), namely ventral hernias in actively or recently infected/contaminated operative fields, and open abdomens in which the native fascia cannot be primarily reapproximated, pose a surgical challenge. Fetal Bovine and Porcine Acellular Dermal Matrix (BADM and PADM) biologic meshes are being increasingly used in these scenarios. A comparison, however, of clinically relevant outcomes between the two is lacking. With this investigation, we aim to review and compare clinically relevant outcomes in patients that underwent abdominal wall herniorrhaphy with either BADM or PADM at a tertiary urban academic institution over a 5-year period. METHODS: Patients who had a BADM or PADM implanted during CVH over a 5-year period at a tertiary urban academic hospital were identified. Baseline clinical and hernia characteristics, as well as postoperative outcomes were compared after a retrospective chart review. Phone interviews were also conducted to assess for recurrence, followed by in-person visits as indicated. Cox Proportional Hazard regression was fitted to identify risk factors for recurrence. RESULTS: Of the 140 patients who underwent biologic mesh implantation for CVH, 109 were for ventral hernia repair and 31 for open abdomen bridging. Mean age was 52.7 ± 14.2 and males constituted 57.9% of our sample, while 25.1% had undergone > 5 prior abdominal operations. Thirty percent were active smokers, and another 30% required emergency surgery. Only immunosuppression was a risk factor for recurrence [HR 13.3 (1.04-169.2), p = 0.047] on Cox Proportional Hazard regression, while mesh selection had no effect. CONCLUSIONS: Both BADM and PADM meshes perform well in CVH, with satisfactory recurrence rates, only slightly higher compared to traditional synthetic mesh repairs.

Duke Scholars

Published In

Eur J Trauma Emerg Surg

DOI

EISSN

1863-9941

Publication Date

June 2022

Volume

48

Issue

3

Start / End Page

1993 / 2001

Location

Germany

Related Subject Headings

  • Treatment Outcome
  • Swine
  • Surgical Mesh
  • Retrospective Studies
  • Recurrence
  • Orthopedics
  • Male
  • Humans
  • Herniorrhaphy
  • Hernia, Ventral
 

Citation

APA
Chicago
ICMJE
MLA
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Van Orden, K., Santos, J., Stanfield, B., Frost, L. S., Ruditsky, A., Foster, A., … Kasotakis, G. (2022). Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging. Eur J Trauma Emerg Surg, 48(3), 1993–2001. https://doi.org/10.1007/s00068-021-01641-z
Van Orden, Kathryn, Jeffrey Santos, Brent Stanfield, Landon S. Frost, Alexander Ruditsky, Andrea Foster, Tejal S. Brahmbhatt, et al. “Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging.Eur J Trauma Emerg Surg 48, no. 3 (June 2022): 1993–2001. https://doi.org/10.1007/s00068-021-01641-z.
Van Orden K, Santos J, Stanfield B, Frost LS, Ruditsky A, Foster A, et al. Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging. Eur J Trauma Emerg Surg. 2022 Jun;48(3):1993–2001.
Van Orden, Kathryn, et al. “Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging.Eur J Trauma Emerg Surg, vol. 48, no. 3, June 2022, pp. 1993–2001. Pubmed, doi:10.1007/s00068-021-01641-z.
Van Orden K, Santos J, Stanfield B, Frost LS, Ruditsky A, Foster A, Brahmbhatt TS, Burke PA, Fernandez-Moure J, Haines K, Agarwal S, Kasotakis G. Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging. Eur J Trauma Emerg Surg. 2022 Jun;48(3):1993–2001.
Journal cover image

Published In

Eur J Trauma Emerg Surg

DOI

EISSN

1863-9941

Publication Date

June 2022

Volume

48

Issue

3

Start / End Page

1993 / 2001

Location

Germany

Related Subject Headings

  • Treatment Outcome
  • Swine
  • Surgical Mesh
  • Retrospective Studies
  • Recurrence
  • Orthopedics
  • Male
  • Humans
  • Herniorrhaphy
  • Hernia, Ventral