Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis.
Publication
, Journal Article
Nickolas, TL; Barasch, J; Mugwanya, KK; Branch, AD; Heffron, R; Wanga, V; Mugo, NR; Ronald, A; Celum, C; Donnell, D; Baeten, JM; Wyatt, CM ...
Published in: AIDS
June 1, 2021
We previously reported a higher incidence of non-albumin proteinuria and a small but significant decline in estimated glomerular filtration rate (eGFR) among HIV-negative adults randomized to emtricitabine/tenofovir disoproxil fumarate preexposure prophylaxis (FTC/TDF PrEP) versus placebo. In a nested case--control study among participants randomized to FTC/TDF PrEP, established kidney injury biomarkers measured at 12 months were not significantly different between participants who subsequently experienced one of these kidney endpoints and randomly selected controls who did not.
Duke Scholars
Published In
AIDS
DOI
EISSN
1473-5571
Publication Date
June 1, 2021
Volume
35
Issue
7
Start / End Page
1147 / 1149
Location
England
Related Subject Headings
- Virology
- Tenofovir
- Pre-Exposure Prophylaxis
- Kidney
- Humans
- HIV Infections
- Emtricitabine
- Biomarkers
- Anti-HIV Agents
- Adult
Citation
APA
Chicago
ICMJE
MLA
NLM
Nickolas, T. L., Barasch, J., Mugwanya, K. K., Branch, A. D., Heffron, R., Wanga, V., … Partners PrEP Study Team. (2021). Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis. AIDS, 35(7), 1147–1149. https://doi.org/10.1097/QAD.0000000000002865
Nickolas, Thomas L., Jonathan Barasch, Kenneth K. Mugwanya, Andrea D. Branch, Renee Heffron, Valentine Wanga, Nelly R. Mugo, et al. “Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis.” AIDS 35, no. 7 (June 1, 2021): 1147–49. https://doi.org/10.1097/QAD.0000000000002865.
Nickolas TL, Barasch J, Mugwanya KK, Branch AD, Heffron R, Wanga V, et al. Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis. AIDS. 2021 Jun 1;35(7):1147–9.
Nickolas, Thomas L., et al. “Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis.” AIDS, vol. 35, no. 7, June 2021, pp. 1147–49. Pubmed, doi:10.1097/QAD.0000000000002865.
Nickolas TL, Barasch J, Mugwanya KK, Branch AD, Heffron R, Wanga V, Mugo NR, Ronald A, Celum C, Donnell D, Baeten JM, Wyatt CM, Partners PrEP Study Team. Kidney injury biomarkers during exposure to tenofovir-based preexposure prophylaxis. AIDS. 2021 Jun 1;35(7):1147–1149.
Published In
AIDS
DOI
EISSN
1473-5571
Publication Date
June 1, 2021
Volume
35
Issue
7
Start / End Page
1147 / 1149
Location
England
Related Subject Headings
- Virology
- Tenofovir
- Pre-Exposure Prophylaxis
- Kidney
- Humans
- HIV Infections
- Emtricitabine
- Biomarkers
- Anti-HIV Agents
- Adult