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Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?

Publication ,  Journal Article
Ramirez, JJ; Bindu, DS; Eroglu, C
Published in: Structure
July 1, 2021

Astrocyte-secreted Hevin induces synapse formation by bridging the trans-synaptic organizers, neuroligins and neurexins. In this issue of Structure, Fan et al. (2021) elucidate the structural basis of Hevin's interaction with these molecules and reveal the competitive interplay between Hevin, SPARC, and MDGAs.

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Published In

Structure

DOI

EISSN

1878-4186

Publication Date

July 1, 2021

Volume

29

Issue

7

Start / End Page

635 / 637

Location

United States

Related Subject Headings

  • Synapses
  • Cell Adhesion Molecules, Neuronal
  • Biophysics
  • 34 Chemical sciences
  • 31 Biological sciences
  • 08 Information and Computing Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences
 

Citation

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Ramirez, J. J., Bindu, D. S., & Eroglu, C. (2021). Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions? Structure, 29(7), 635–637. https://doi.org/10.1016/j.str.2021.06.011
Ramirez, Juan J., Dhanesh Sivadasan Bindu, and Cagla Eroglu. “Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?Structure 29, no. 7 (July 1, 2021): 635–37. https://doi.org/10.1016/j.str.2021.06.011.
Ramirez, Juan J., et al. “Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?Structure, vol. 29, no. 7, July 2021, pp. 635–37. Pubmed, doi:10.1016/j.str.2021.06.011.
Journal cover image

Published In

Structure

DOI

EISSN

1878-4186

Publication Date

July 1, 2021

Volume

29

Issue

7

Start / End Page

635 / 637

Location

United States

Related Subject Headings

  • Synapses
  • Cell Adhesion Molecules, Neuronal
  • Biophysics
  • 34 Chemical sciences
  • 31 Biological sciences
  • 08 Information and Computing Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences