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Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast.

Publication ,  Journal Article
Zhu, C; Haraldsson, H; Kallianos, K; Ge, L; Tseng, E; Henry, T; Saloner, D; Hope, MD
Published in: Int J Cardiovasc Imaging
March 2018

Both noncontrast and contrast-enhanced approaches to gated thoracic magnetic resonance angiography (MRA) for aortic root evaluation have been reported at 3T. We compare qualitative and quantitative image quality measures for the two approaches, and assess the reproducibility of standard aortic measurements. Respiratory and cardiac gated MRA of the chest was performed at 3T in 45 patients: 23 after administration of iron-based blood pool contrast, and 22 without contrast. Image quality was assessed with a 5-point Likert scale, vessel lumen-to-muscle contrast ratios, and vessel wall sharpness. Two reviewers measured the ascending aorta diameter and valve annulus area. Interrater agreement was assessed using Bland-Altman plots and coefficient of variation (CV). Qualitative image quality was better with blood pool contrast in all principal vessels of the chest (mean Likert of 4.20 ± 0.79 vs. 2.60 ± 0.77, p < 0.001). Quantitative assessment was also improved with higher contrast ratios in all vessels (5.26 ± 3.3 vs. 1.90 ± 0.53, p < 0.001), and greater sharpness of the aortic annulus and ascending aorta (0.70 ± 0.16 vs. 0.56 ± 0.14 mm-1, p < 0.001, and 0.87 ± 0.16 vs. 0.62 ± 0.16 mm-1, p = 0.008, respectively). Reproducibility of measurement was marginally better for the ascending aorta diameter (CV of 2.80 vs. 3.23%), but substantially increased for the aortic valve annulus area with blood pool contrast (CV of 4.93 vs. 7.32%). The use of a blood pool contrast agent for gated thoracic MRA improves image quality compared to a noncontrast technique, and provides more reproducible measurements of the aortic valve annulus area.

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Published In

Int J Cardiovasc Imaging

DOI

EISSN

1875-8312

Publication Date

March 2018

Volume

34

Issue

3

Start / End Page

475 / 483

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Reproducibility of Results
  • Predictive Value of Tests
  • Observer Variation
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Angiography
  • Humans
  • Ferrosoferric Oxide
 

Citation

APA
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Zhu, C., Haraldsson, H., Kallianos, K., Ge, L., Tseng, E., Henry, T., … Hope, M. D. (2018). Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging, 34(3), 475–483. https://doi.org/10.1007/s10554-017-1242-8
Zhu, Chengcheng, Henrik Haraldsson, Kimberly Kallianos, Liang Ge, Elaine Tseng, Travis Henry, David Saloner, and Michael D. Hope. “Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast.Int J Cardiovasc Imaging 34, no. 3 (March 2018): 475–83. https://doi.org/10.1007/s10554-017-1242-8.
Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, et al. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging. 2018 Mar;34(3):475–83.
Zhu, Chengcheng, et al. “Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast.Int J Cardiovasc Imaging, vol. 34, no. 3, Mar. 2018, pp. 475–83. Pubmed, doi:10.1007/s10554-017-1242-8.
Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, Saloner D, Hope MD. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging. 2018 Mar;34(3):475–483.

Published In

Int J Cardiovasc Imaging

DOI

EISSN

1875-8312

Publication Date

March 2018

Volume

34

Issue

3

Start / End Page

475 / 483

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Reproducibility of Results
  • Predictive Value of Tests
  • Observer Variation
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Angiography
  • Humans
  • Ferrosoferric Oxide