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The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme.

Publication ,  Journal Article
Schwarzman, LS; Abern, MR; Garvey, DF; Andriole, GL; Freedland, SJ; Moreira, DM
Published in: J Urol
November 2018

PURPOSE: Prostate biopsy complications have important consequences that may affect patient compliance with rebiopsy schemes. However, to our knowledge this has not been studied in earnest. Thus, we evaluated whether previous prostate biopsy related complications and the type of complication were associated with repeat prostate biopsy compliance in a clinical trial with study mandated systematic biopsies. MATERIALS AND METHODS: We retrospectively analyzed the records of 4,939 men 50 to 75 years old who underwent 2-year prostate biopsy and were recommended to undergo 4-year prostate rebiopsy in the REDUCE (Reduction by Dutasteride of Prostate Cancer Events) study. The analyzed biopsy complications were hematuria, urinary tract infection, acute urinary retention and hemospermia. RESULTS: A total of 260 men (5.3%) had a 2-year prostate biopsy related complication, including hematuria in 180 (3.6%), urinary tract infection in 36 (0.7%), acute urinary retention in 26 (0.5%) and hemospermia in 102 (2.1%). A total of 474 men (9.6%) were noncompliant with 4-year rebiopsy. On univariable analysis any previous complication (OR 1.56, 95% CI 1.08-2.24, p = 0.018), urinary tract infection (OR 2.72, 95% CI 1.23-6.00, p = 0.013), acute urinary retention (OR 4.24, 95% CI 1.83-9.81, p = 0.016) and hemospermia (OR 1.78, 95% CI 1.03-3.06, p = 0.037) were associated with rebiopsy noncompliance. Hematuria was not associated with rebiopsy noncompliance (OR 1.19, 95% CI 0.74-1.91, p = 0.483). Results were unchanged on multivariable analysis, including for any complication (OR 1.65, 95% CI 1.08-2.26, p = 0.018), for urinary tract infection (OR 2.62, 95% CI 1.07-3.21, p = 0.029), for acute urinary retention (OR 4.51, 95% CI 1.93-10.54, p = 0.001), for hemospermia (OR 1.85, 95% CI 1.07-3.21, p = 0.029) and for hematuria (OR 1.19, 95% CI 0.74-1.93, p = 0.472). CONCLUSIONS: In men who undergo repeat prostate biopsy a previous biopsy related complication and the type of complication were associated with lower compliance with rebiopsy schemes. Patients who experience biopsy related complications are ideal candidates to receive intervention regarding the importance of prostate rebiopsy to prevent noncompliance.

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Published In

J Urol

DOI

EISSN

1527-3792

Publication Date

November 2018

Volume

200

Issue

5

Start / End Page

1062 / 1067

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Urinary Tract Infections
  • Urinary Retention
  • Treatment Outcome
  • Retrospective Studies
  • Reoperation
  • Prostatic Neoplasms
  • Prostate
  • Postoperative Complications
  • Patient Education as Topic
 

Citation

APA
Chicago
ICMJE
MLA
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Schwarzman, L. S., Abern, M. R., Garvey, D. F., Andriole, G. L., Freedland, S. J., & Moreira, D. M. (2018). The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme. J Urol, 200(5), 1062–1067. https://doi.org/10.1016/j.juro.2018.06.018
Schwarzman, Logan S., Michael R. Abern, Daniel F. Garvey, Gerald L. Andriole, Stephen J. Freedland, and Daniel M. Moreira. “The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme.J Urol 200, no. 5 (November 2018): 1062–67. https://doi.org/10.1016/j.juro.2018.06.018.
Schwarzman LS, Abern MR, Garvey DF, Andriole GL, Freedland SJ, Moreira DM. The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme. J Urol. 2018 Nov;200(5):1062–7.
Schwarzman, Logan S., et al. “The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme.J Urol, vol. 200, no. 5, Nov. 2018, pp. 1062–67. Pubmed, doi:10.1016/j.juro.2018.06.018.
Schwarzman LS, Abern MR, Garvey DF, Andriole GL, Freedland SJ, Moreira DM. The Association of Previous Prostate Biopsy Related Complications and the Type of Complication with Patient Compliance with Rebiopsy Scheme. J Urol. 2018 Nov;200(5):1062–1067.
Journal cover image

Published In

J Urol

DOI

EISSN

1527-3792

Publication Date

November 2018

Volume

200

Issue

5

Start / End Page

1062 / 1067

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Urinary Tract Infections
  • Urinary Retention
  • Treatment Outcome
  • Retrospective Studies
  • Reoperation
  • Prostatic Neoplasms
  • Prostate
  • Postoperative Complications
  • Patient Education as Topic