The Long Neglected Cycloidal Mass Analyzer.
In 1938, Walker Bleakney and John A. Hipple first described the cycloidal mass analyzer as the only mass analyzer configuration capable of "perfect" ion focusing. Why has their geometry been largely neglected for many years and how might it earn a respectable place in the world of modern chemical analysis? This Perspective explores the properties of the cycloidal mass analyzer and identifies the lack of suitable ion array detectors as a significant reason why cycloidal mass analyzers are not widely used. The recent development of capacitive transimpedance amplifier array detectors can enable several techniques using cycloidal mass analyzers including spatially coded apertures and single particle mass analysis with a "virtual-slit", helping the cycloidal mass analyzer earn a respectable place in chemical analysis.
Duke Scholars
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- Analytical Chemistry
- Amplifiers, Electronic
- 4004 Chemical engineering
- 3401 Analytical chemistry
- 3205 Medical biochemistry and metabolomics
- 0399 Other Chemical Sciences
- 0301 Analytical Chemistry
Citation
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Analytical Chemistry
- Amplifiers, Electronic
- 4004 Chemical engineering
- 3401 Analytical chemistry
- 3205 Medical biochemistry and metabolomics
- 0399 Other Chemical Sciences
- 0301 Analytical Chemistry