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Precision Medicine and PET-Computed Tomography in Pediatric Malignancies.

Publication ,  Journal Article
Sanli, Y; Yilmaz, E; Subramaniam, RM
Published in: PET Clin
October 2017

Fluorine-18 fluorodeoxyglucose (18F-FDG) PET-computed tomography (CT) plays a significant role in diagnosis, staging, therapy selection, and therapy assessment of multiple pediatric malignancies and facilitating precision medicine delivery in pediatric patients. In patients with Hodgkin lymphoma, interim fludeoxyglucose 18F-FDG PET/CT is highly sensitive and specific for predicting survival and multiple trials with FDG PET/CT-based adaptive therapies are currently ongoing. It is superior to iodine-131 metaiodobenzylguanidine (131I-MIBG) scintigraphy and bone scintigraphy for detecting metastases in neuroblastoma patients and sarcoma patients. It may predict histologic differentiation and neoadjuvant therapy assessment in Wilms tumor.

Duke Scholars

Published In

PET Clin

DOI

EISSN

1879-9809

Publication Date

October 2017

Volume

12

Issue

4

Start / End Page

423 / 435

Location

United States

Related Subject Headings

  • Radiopharmaceuticals
  • Precision Medicine
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Humans
  • Fluorodeoxyglucose F18
  • Child
  • 3211 Oncology and carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sanli, Y., Yilmaz, E., & Subramaniam, R. M. (2017). Precision Medicine and PET-Computed Tomography in Pediatric Malignancies. PET Clin, 12(4), 423–435. https://doi.org/10.1016/j.cpet.2017.05.009
Sanli, Yasemin, Ebru Yilmaz, and Rathan M. Subramaniam. “Precision Medicine and PET-Computed Tomography in Pediatric Malignancies.PET Clin 12, no. 4 (October 2017): 423–35. https://doi.org/10.1016/j.cpet.2017.05.009.
Sanli Y, Yilmaz E, Subramaniam RM. Precision Medicine and PET-Computed Tomography in Pediatric Malignancies. PET Clin. 2017 Oct;12(4):423–35.
Sanli, Yasemin, et al. “Precision Medicine and PET-Computed Tomography in Pediatric Malignancies.PET Clin, vol. 12, no. 4, Oct. 2017, pp. 423–35. Pubmed, doi:10.1016/j.cpet.2017.05.009.
Sanli Y, Yilmaz E, Subramaniam RM. Precision Medicine and PET-Computed Tomography in Pediatric Malignancies. PET Clin. 2017 Oct;12(4):423–435.
Journal cover image

Published In

PET Clin

DOI

EISSN

1879-9809

Publication Date

October 2017

Volume

12

Issue

4

Start / End Page

423 / 435

Location

United States

Related Subject Headings

  • Radiopharmaceuticals
  • Precision Medicine
  • Positron Emission Tomography Computed Tomography
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Humans
  • Fluorodeoxyglucose F18
  • Child
  • 3211 Oncology and carcinogenesis