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Perceived Discrimination and Symptoms of Cognitive Dysfuntion Among Middle-Age and Older Persons Living With HIV in China: A Multicenter Cross-Sectional Study of the Mediating Role of Mental Health Symptoms and Social Isolation.

Publication ,  Journal Article
Han, S; Hu, Y; Wang, L; Pei, Y; Zhu, Z; Qi, X; Wu, B
Published in: The Journal of the Association of Nurses in AIDS Care : JANAC
July 2021

Perceived discrimination is associated with symptoms of cognitive dysfunction (SOCD) among middle-age and older persons living with HIV (PLWH). We aimed to explore how the association between perceived discrimination and SOCD was mediated by mental health symptoms and social isolation. The sample included 321 PLWH, ages 45 years and older, for a multicenter cross-sectional study. Structural equation modeling showed an acceptable model fit and a significant total indirect effect between perceived discrimination and SOCD. All three indirect effect pathways were significant, suggesting that perceived discrimination could influence SOCD through mental health symptoms, through social isolation, or through mental health symptoms and then social isolation. Our study demonstrates that perceived discrimination is a concern for the management of cognitive function among middle-age and older PLWH. Both mental health symptoms and social isolation are critical elements in the design and evaluation of interventions for promoting cognitive health.

Duke Scholars

Published In

The Journal of the Association of Nurses in AIDS Care : JANAC

DOI

EISSN

1552-6917

ISSN

1055-3290

Publication Date

July 2021

Volume

32

Issue

4

Start / End Page

442 / 452

Related Subject Headings

  • Social Isolation
  • Public Health
  • Middle Aged
  • Mental Health
  • Humans
  • HIV Infections
  • Cross-Sectional Studies
  • Cognition
  • Aged, 80 and over
  • Aged
 

Citation

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ICMJE
MLA
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Han, S., Hu, Y., Wang, L., Pei, Y., Zhu, Z., Qi, X., & Wu, B. (2021). Perceived Discrimination and Symptoms of Cognitive Dysfuntion Among Middle-Age and Older Persons Living With HIV in China: A Multicenter Cross-Sectional Study of the Mediating Role of Mental Health Symptoms and Social Isolation. The Journal of the Association of Nurses in AIDS Care : JANAC, 32(4), 442–452. https://doi.org/10.1097/jnc.0000000000000264
Han, Shuyu, Yan Hu, Lina Wang, Yaolin Pei, Zheng Zhu, Xiang Qi, and Bei Wu. “Perceived Discrimination and Symptoms of Cognitive Dysfuntion Among Middle-Age and Older Persons Living With HIV in China: A Multicenter Cross-Sectional Study of the Mediating Role of Mental Health Symptoms and Social Isolation.The Journal of the Association of Nurses in AIDS Care : JANAC 32, no. 4 (July 2021): 442–52. https://doi.org/10.1097/jnc.0000000000000264.
Han, Shuyu, et al. “Perceived Discrimination and Symptoms of Cognitive Dysfuntion Among Middle-Age and Older Persons Living With HIV in China: A Multicenter Cross-Sectional Study of the Mediating Role of Mental Health Symptoms and Social Isolation.The Journal of the Association of Nurses in AIDS Care : JANAC, vol. 32, no. 4, July 2021, pp. 442–52. Epmc, doi:10.1097/jnc.0000000000000264.
Journal cover image

Published In

The Journal of the Association of Nurses in AIDS Care : JANAC

DOI

EISSN

1552-6917

ISSN

1055-3290

Publication Date

July 2021

Volume

32

Issue

4

Start / End Page

442 / 452

Related Subject Headings

  • Social Isolation
  • Public Health
  • Middle Aged
  • Mental Health
  • Humans
  • HIV Infections
  • Cross-Sectional Studies
  • Cognition
  • Aged, 80 and over
  • Aged