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Evolving symptom networks in relation to HIV-positive duration among people living with HIV: A network analysis.

Publication ,  Journal Article
Zhu, Z; Wen, H; Yang, Z; Han, S; Fu, Y; Zhang, L; Hu, Y; Wu, B
Published in: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
July 2021

To explore and visualize the relationships among multiple symptoms in people living with HIV (PLWH) and compare centrality indices and the density of symptom networks among groups of individuals with different HIV-positive durations.We conducted a secondary analysis of data from the HIV-related Symptoms Monitoring Survey conducted in China. Networks were constructed among 27 symptoms. Centrality properties, including strength and closeness, and network density were used to describe relationships among symptoms in 5 different HIV-positive duration groups.The findings showed that PLWH with longer HIV-positive durations did not have more severe symptoms; instead, their symptom networks were denser than those of their newly HIV-diagnosed counterparts (F = 27.073, P < 0.001). Fatigue was the most severe and central symptom in PLWH with an HIV-positive duration <10 years (rS = 7.79-10.09, rB = 18-44, rC = 0.01). Confusion was the most central symptom across the 3 centrality indices (rS = 11.81, rB = 14.00, rC = 0.02) in PLWH who had HIV-positive durations >10 years.This study demonstrates a need to include an assessment of PLWH symptom networks as an essential component of HIV care. We recommended evaluating cognitive function and cognitive training as essential components of HIV care for long-term survivors, even in younger populations (aged ≤50 years).

Duke Scholars

Published In

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

DOI

EISSN

1878-3511

ISSN

1201-9712

Publication Date

July 2021

Volume

108

Start / End Page

503 / 509

Related Subject Headings

  • Middle Aged
  • Microbiology
  • Male
  • Humans
  • Health Surveys
  • HIV Seropositivity
  • HIV Infections
  • Female
  • Fatigue
  • Confusion
 

Citation

APA
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MLA
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Zhu, Z., Wen, H., Yang, Z., Han, S., Fu, Y., Zhang, L., … Wu, B. (2021). Evolving symptom networks in relation to HIV-positive duration among people living with HIV: A network analysis. International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, 108, 503–509. https://doi.org/10.1016/j.ijid.2021.05.084
Zhu, Zheng, Huan Wen, Zhongfang Yang, Shuyu Han, Yanfen Fu, Lin Zhang, Yan Hu, and Bei Wu. “Evolving symptom networks in relation to HIV-positive duration among people living with HIV: A network analysis.International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases 108 (July 2021): 503–9. https://doi.org/10.1016/j.ijid.2021.05.084.
Zhu Z, Wen H, Yang Z, Han S, Fu Y, Zhang L, et al. Evolving symptom networks in relation to HIV-positive duration among people living with HIV: A network analysis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2021 Jul;108:503–9.
Zhu, Zheng, et al. “Evolving symptom networks in relation to HIV-positive duration among people living with HIV: A network analysis.International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases, vol. 108, July 2021, pp. 503–09. Epmc, doi:10.1016/j.ijid.2021.05.084.
Zhu Z, Wen H, Yang Z, Han S, Fu Y, Zhang L, Hu Y, Wu B. Evolving symptom networks in relation to HIV-positive duration among people living with HIV: A network analysis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2021 Jul;108:503–509.

Published In

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

DOI

EISSN

1878-3511

ISSN

1201-9712

Publication Date

July 2021

Volume

108

Start / End Page

503 / 509

Related Subject Headings

  • Middle Aged
  • Microbiology
  • Male
  • Humans
  • Health Surveys
  • HIV Seropositivity
  • HIV Infections
  • Female
  • Fatigue
  • Confusion