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Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore-analysis of the SingHealth Diabetes Registry.

Publication ,  Journal Article
Feng, L; Lam, A; Carmody, D; Lim, CW; Tan, G; Goh, S-Y; Bee, YM; Jafar, TH
Published in: PloS one
January 2021

Asian populations are at high risk of diabetes and related vascular complications. We examined risk factor control, preventive care, and disparities in these trends among adults with diabetes in Singapore.The sample included 209,930 adults with diabetes aged≥18 years from a multi-institutional SingHealth Diabetes Registry between 2013 and 2019 in Singapore. We performed logistic generalized estimating equations (GEEs) regression analysis and used linear mixed effect modeling to evaluate the temporal trends.Between 2013 and 2019, the unadjusted control rates of glycated hemoglobin (4.8%, 95%CI (4.4 to 5.1) and low-density lipoprotein cholesterol (LDL-C) (11.5%, 95%CI (11.1 to 11.8)) improved, but blood pressure (BP) control worsened (systolic BP (SBP)/diastolic BP (DBP) <140/90 mmHg: -6.6%, 95%CI (-7.0 to -6.2)). These trends persisted after accounting for the demographics including age, gender, ethnicity, and housing type. The 10-year adjusted risk for coronary heart disease (CHD) (3.4%, 95% (3.3 to 3.5)) and stroke (10.4%, 95% CI (10.3 to 10.5)) increased. In 2019, the control rates of glycated hemoglobin, BP (SBP/DBP<140/90 mmHg), LDL-C, each, and all three risk factors together, accounted for 51.5%, 67.7%, 72.2%, and 24.4%, respectively.Trends in risk factor control improved for glycated hemoglobin and LDL-C, but worsened for BP among diabetic adults in Singapore from 2013 to 2019. Control rates for all risk factors remain inadequate.

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Published In

PloS one

DOI

EISSN

1932-6203

ISSN

1932-6203

Publication Date

January 2021

Volume

16

Issue

11

Start / End Page

e0259157

Related Subject Headings

  • Young Adult
  • Singapore
  • Retrospective Studies
  • Registries
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Heart Disease Risk Factors
  • Glycated Hemoglobin
 

Citation

APA
Chicago
ICMJE
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Feng, L., Lam, A., Carmody, D., Lim, C. W., Tan, G., Goh, S.-Y., … Jafar, T. H. (2021). Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore-analysis of the SingHealth Diabetes Registry. PloS One, 16(11), e0259157. https://doi.org/10.1371/journal.pone.0259157
Feng, Liang, Amanda Lam, David Carmody, Ching Wee Lim, Gilbert Tan, Su-Yen Goh, Yong Mong Bee, and Tazeen H. Jafar. “Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore-analysis of the SingHealth Diabetes Registry.PloS One 16, no. 11 (January 2021): e0259157. https://doi.org/10.1371/journal.pone.0259157.
Feng, Liang, et al. “Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore-analysis of the SingHealth Diabetes Registry.PloS One, vol. 16, no. 11, Jan. 2021, p. e0259157. Epmc, doi:10.1371/journal.pone.0259157.
Feng L, Lam A, Carmody D, Lim CW, Tan G, Goh S-Y, Bee YM, Jafar TH. Trends in cardiovascular risk factors and treatment goals in patients with diabetes in Singapore-analysis of the SingHealth Diabetes Registry. PloS one. 2021 Jan;16(11):e0259157.

Published In

PloS one

DOI

EISSN

1932-6203

ISSN

1932-6203

Publication Date

January 2021

Volume

16

Issue

11

Start / End Page

e0259157

Related Subject Headings

  • Young Adult
  • Singapore
  • Retrospective Studies
  • Registries
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Heart Disease Risk Factors
  • Glycated Hemoglobin