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The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section.

Publication ,  Journal Article
Alhazzani, W; Alshahrani, M; Alshamsi, F; Aljuhani, O; Eljaaly, K; Hashim, S; Alqahtani, R; Alsaleh, D; Al Duhailib, Z; Algethamy, H; Dahhan, T ...
Published in: J Infect Public Health
January 2022

BACKGROUND: The rapid increase in coronavirus disease 2019 (COVID-19) cases during the subsequent waves in Saudi Arabia and other countries prompted the Saudi Critical Care Society (SCCS) to put together a panel of experts to issue evidence-based recommendations for the management of COVID-19 in the intensive care unit (ICU). METHODS: The SCCS COVID-19 panel included 51 experts with expertise in critical care, respirology, infectious disease, epidemiology, emergency medicine, clinical pharmacy, nursing, respiratory therapy, methodology, and health policy. All members completed an electronic conflict of interest disclosure form. The panel addressed 9 questions that are related to the therapy of COVID-19 in the ICU. We identified relevant systematic reviews and clinical trials, then used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach as well as the evidence-to-decision framework (EtD) to assess the quality of evidence and generate recommendations. RESULTS: The SCCS COVID-19 panel issued 12 recommendations on pharmacotherapeutic interventions (immunomodulators, antiviral agents, and anticoagulants) for severe and critical COVID-19, of which 3 were strong recommendations and 9 were weak recommendations. CONCLUSION: The SCCS COVID-19 panel used the GRADE approach to formulate recommendations on therapy for COVID-19 in the ICU. The EtD framework allows adaptation of these recommendations in different contexts. The SCCS guideline committee will update recommendations as new evidence becomes available.

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Published In

J Infect Public Health

DOI

EISSN

1876-035X

Publication Date

January 2022

Volume

15

Issue

1

Start / End Page

142 / 151

Location

England

Related Subject Headings

  • Saudi Arabia
  • SARS-CoV-2
  • Intensive Care Units
  • Humans
  • Critical Care
  • COVID-19
  • 4206 Public health
  • 4202 Epidemiology
  • 3202 Clinical sciences
  • 1199 Other Medical and Health Sciences
 

Citation

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Alhazzani, W., Alshahrani, M., Alshamsi, F., Aljuhani, O., Eljaaly, K., Hashim, S., … Al-Jedai, A. (2022). The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section. J Infect Public Health, 15(1), 142–151. https://doi.org/10.1016/j.jiph.2021.10.005
Alhazzani, Waleed, Mohammed Alshahrani, Fayez Alshamsi, Ohoud Aljuhani, Khalid Eljaaly, Samaher Hashim, Rakan Alqahtani, et al. “The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section.J Infect Public Health 15, no. 1 (January 2022): 142–51. https://doi.org/10.1016/j.jiph.2021.10.005.
Alhazzani W, Alshahrani M, Alshamsi F, Aljuhani O, Eljaaly K, Hashim S, et al. The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section. J Infect Public Health. 2022 Jan;15(1):142–51.
Alhazzani, Waleed, et al. “The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section.J Infect Public Health, vol. 15, no. 1, Jan. 2022, pp. 142–51. Pubmed, doi:10.1016/j.jiph.2021.10.005.
Alhazzani W, Alshahrani M, Alshamsi F, Aljuhani O, Eljaaly K, Hashim S, Alqahtani R, Alsaleh D, Al Duhailib Z, Algethamy H, Al-Musawi T, Alshammari T, Alqarni A, Khoujah D, Tashkandi W, Dahhan T, Almutairi N, Alserehi HA, Al-Yahya M, Al-Judaibi B, Arabi YM, Abualenain J, Alotaibi JM, Al Bshabshe A, Alharbi R, Al-Hameed F, Elhazmi A, Almaghrabi RS, Almaghlouth F, Abedalthagafi M, Al Khathlan N, Al-Suwaidan FA, Bunyan RF, Baw B, Alghamdi G, Al Hazmi M, Mandourah Y, Assiri A, Enani M, Alawi M, Aljindan R, Aljabbary A, Alrbiaan A, Algurashi F, Alsaawi A, Alenazi TH, Alsultan MA, Alqahtani SA, Memish Z, Al-Tawfiq JA, Al-Jedai A. The Saudi Critical Care Society practice guidelines on the management of COVID-19 in the ICU: Therapy section. J Infect Public Health. 2022 Jan;15(1):142–151.

Published In

J Infect Public Health

DOI

EISSN

1876-035X

Publication Date

January 2022

Volume

15

Issue

1

Start / End Page

142 / 151

Location

England

Related Subject Headings

  • Saudi Arabia
  • SARS-CoV-2
  • Intensive Care Units
  • Humans
  • Critical Care
  • COVID-19
  • 4206 Public health
  • 4202 Epidemiology
  • 3202 Clinical sciences
  • 1199 Other Medical and Health Sciences