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Body mass index affects outcomes after vertebral body tethering surgery.

Publication ,  Journal Article
Mishreky, A; Parent, S; Miyanji, F; Smit, K; Murphy, J; Bowker, R; Al Khatib, N; El-Hawary, R; Pediatric Spine Study Group,
Published in: Spine Deform
May 2022

PURPOSE: To compare the outcomes of anterior Vertebral Body Tethering (AVBT) surgery between overweight and non-overweight patients. METHODS: AIS/JIS patients with AVBT with 2-year follow-up from a multi-center pediatric spine database were evaluated pre-operatively, 1st post-operative erect, and 2 years post-operatively. ANOVA was used to compare 3 categories of BMI with significance as per Tukey-Kramer HSD post hoc test. Risk of scoliosis progression was analysed with Mid-P exact test. RESULTS: 121 patients (51 underweight, 58 normal, 12 overweight; mean age 12.5 ± 1.6 yr; BMI 18.8 ± 4.6 kg/m2) were identified. Comparing underweight, normal, and overweight groups: mean pre-operative age (13 yr, 13 yr, 12 yr), scoliosis (52°, 50°, 52°), pre-operative kyphosis (29°, 28°, 33°), peri-operative scoliosis correction (44%, 42%, 46%), and complications by 2-year follow-up (23%, 24%, 17%) were similar between groups. There was one broken tether in each of the underweight and normal weight groups. Change in percent scoliosis correction from 1st erect to 2-year post-operative (i.e., growth modulation phase) was not significantly different between groups; however, the risk ratio for scoliosis progression during this period was 4.74 (1.02-22.02; p = 0.04) for overweight patients. CONCLUSION: Our findings demonstrate that, as compared to normal weight and underweight patients, overweight patients did not have a statistically significant difference in intra-operative scoliosis correction or in risk of experiencing complication; however, overweight patients had a risk ratio of 4.74 for progression of scoliosis during the growth modulation phase of treatment from first erect radiographs to minimum 2-year follow-up. LEVEL OF EVIDENCE: III.

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Published In

Spine Deform

DOI

EISSN

2212-1358

Publication Date

May 2022

Volume

10

Issue

3

Start / End Page

563 / 571

Location

England

Related Subject Headings

  • Vertebral Body
  • Treatment Outcome
  • Thoracic Vertebrae
  • Thinness
  • Scoliosis
  • Retrospective Studies
  • Overweight
  • Humans
  • Child
  • Body Mass Index
 

Citation

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Chicago
ICMJE
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Mishreky, A., Parent, S., Miyanji, F., Smit, K., Murphy, J., Bowker, R., … Pediatric Spine Study Group, . (2022). Body mass index affects outcomes after vertebral body tethering surgery. Spine Deform, 10(3), 563–571. https://doi.org/10.1007/s43390-021-00455-8
Mishreky, Amir, Stefan Parent, Firoz Miyanji, Kevin Smit, Joshua Murphy, Riley Bowker, Nedal Al Khatib, Ron El-Hawary, and Ron Pediatric Spine Study Group. “Body mass index affects outcomes after vertebral body tethering surgery.Spine Deform 10, no. 3 (May 2022): 563–71. https://doi.org/10.1007/s43390-021-00455-8.
Mishreky A, Parent S, Miyanji F, Smit K, Murphy J, Bowker R, et al. Body mass index affects outcomes after vertebral body tethering surgery. Spine Deform. 2022 May;10(3):563–71.
Mishreky, Amir, et al. “Body mass index affects outcomes after vertebral body tethering surgery.Spine Deform, vol. 10, no. 3, May 2022, pp. 563–71. Pubmed, doi:10.1007/s43390-021-00455-8.
Mishreky A, Parent S, Miyanji F, Smit K, Murphy J, Bowker R, Al Khatib N, El-Hawary R, Pediatric Spine Study Group. Body mass index affects outcomes after vertebral body tethering surgery. Spine Deform. 2022 May;10(3):563–571.
Journal cover image

Published In

Spine Deform

DOI

EISSN

2212-1358

Publication Date

May 2022

Volume

10

Issue

3

Start / End Page

563 / 571

Location

England

Related Subject Headings

  • Vertebral Body
  • Treatment Outcome
  • Thoracic Vertebrae
  • Thinness
  • Scoliosis
  • Retrospective Studies
  • Overweight
  • Humans
  • Child
  • Body Mass Index