Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.
Publication
, Journal Article
Baker, LG; Specht, CA; Lodge, JK
Published in: Eukaryot Cell
September 2011
Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan. Multiple genetic approaches have defined a chitosan-deficient syndrome that includes slow growth and decreased cell integrity. Here we demonstrate chitosan is necessary for virulence and persistence in the mammalian host.
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Published In
Eukaryot Cell
DOI
EISSN
1535-9786
Publication Date
September 2011
Volume
10
Issue
9
Start / End Page
1264 / 1268
Location
United States
Related Subject Headings
- Virulence
- Mutation
- Microbiology
- Mice
- Glucans
- Gene Expression Regulation, Fungal
- Fungal Proteins
- Cryptococcus neoformans
- Cryptococcosis
- Chitosan
Citation
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Chicago
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MLA
NLM
Baker, L. G., Specht, C. A., & Lodge, J. K. (2011). Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell, 10(9), 1264–1268. https://doi.org/10.1128/EC.05138-11
Baker, Lorina G., Charles A. Specht, and Jennifer K. Lodge. “Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.” Eukaryot Cell 10, no. 9 (September 2011): 1264–68. https://doi.org/10.1128/EC.05138-11.
Baker LG, Specht CA, Lodge JK. Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell. 2011 Sep;10(9):1264–8.
Baker, Lorina G., et al. “Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans.” Eukaryot Cell, vol. 10, no. 9, Sept. 2011, pp. 1264–68. Pubmed, doi:10.1128/EC.05138-11.
Baker LG, Specht CA, Lodge JK. Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell. 2011 Sep;10(9):1264–1268.
Published In
Eukaryot Cell
DOI
EISSN
1535-9786
Publication Date
September 2011
Volume
10
Issue
9
Start / End Page
1264 / 1268
Location
United States
Related Subject Headings
- Virulence
- Mutation
- Microbiology
- Mice
- Glucans
- Gene Expression Regulation, Fungal
- Fungal Proteins
- Cryptococcus neoformans
- Cryptococcosis
- Chitosan