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Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation.

Publication ,  Journal Article
National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation,
Published in: Am J Kidney Dis
February 2022

Despite the high prevalence and economic burden of chronic kidney disease (CKD) in the United States, federal funding for kidney-related research, prevention, and education activities under the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) remains substantially lower compared to other chronic diseases. More federal support is needed to promote critical research that will expand knowledge of kidney health and disease, develop new and effective therapies, and reduce health disparities. In 2021, the National Kidney Foundation (NKF) convened 2 Research Roundtables (preclinical and clinical research), comprising nephrology leaders from prominent US academic institutions and the pharmaceutical industry, key bodies with expertise in research, and including individuals with CKD and their caregivers and kidney donors. The goal of these roundtables was to identify priorities for preclinical and clinical kidney-related research. The research priorities identified by the Research Roundtables and presented in this position statement outline attainable opportunities for groundbreaking and critically needed innovations that will benefit patients with kidney disease in the next 5-10 years. Research priorities fall within 4 preclinical science themes (expand data science capability, define kidney disease mechanisms and utilize genetic tools to identify new therapeutic targets, develop better models of human disease, and test cell-specific drug delivery systems and utilize gene editing) and 3 clinical science themes (expand number and inclusivity of clinical trials, develop and test interventions to reduce health disparities, and support implementation science). These priorities in kidney-related research, if supported by additional funding by federal agencies, will increase our understanding of the development and progression of kidney disease among diverse populations, attract additional industry investment, and lead to new and more personalized treatments.

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Published In

Am J Kidney Dis

DOI

EISSN

1523-6838

Publication Date

February 2022

Volume

79

Issue

2

Start / End Page

141 / 152

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • United States
  • Research
  • Renal Insufficiency, Chronic
  • Nephrology
  • Kidney
  • Humans
  • Diabetic Nephropathies
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
 

Citation

APA
Chicago
ICMJE
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National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation, . (2022). Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation. Am J Kidney Dis, 79(2), 141–152. https://doi.org/10.1053/j.ajkd.2021.08.018
National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation, Justin. “Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation.Am J Kidney Dis 79, no. 2 (February 2022): 141–52. https://doi.org/10.1053/j.ajkd.2021.08.018.
National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation. Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation. Am J Kidney Dis. 2022 Feb;79(2):141–52.
National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation, Justin. “Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation.Am J Kidney Dis, vol. 79, no. 2, Feb. 2022, pp. 141–52. Pubmed, doi:10.1053/j.ajkd.2021.08.018.
National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation. Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation. Am J Kidney Dis. 2022 Feb;79(2):141–152.
Journal cover image

Published In

Am J Kidney Dis

DOI

EISSN

1523-6838

Publication Date

February 2022

Volume

79

Issue

2

Start / End Page

141 / 152

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • United States
  • Research
  • Renal Insufficiency, Chronic
  • Nephrology
  • Kidney
  • Humans
  • Diabetic Nephropathies
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services