Comprehensive Toxicology: Second Edition
Physiological and Pathological Functions of Mammalian MicroRNAs
Publication
, Chapter
Liu, MF; Jiang, S; Lu, Z; Li, Y; Young, KH
January 1, 2010
MicroRNAs (miRNAs) are 19- to 26-nucleotide RNAs that regulate gene expression. Over 700 human miRNA genes have been identified, with one report predicting close to 1000. Recent computational methods indicate that up to 92% of human genes may be regulated by miRNA. In this chapter, we discuss recent progress in miRNA biology and their roles in human disease pathogenesis, as well as opportunities and challenges of miRNA-based therapies.
Duke Scholars
DOI
Publication Date
January 1, 2010
Volume
2-14
Start / End Page
427 / 446
Citation
APA
Chicago
ICMJE
MLA
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Liu, M. F., Jiang, S., Lu, Z., Li, Y., & Young, K. H. (2010). Physiological and Pathological Functions of Mammalian MicroRNAs. In Comprehensive Toxicology: Second Edition (Vol. 2–14, pp. 427–446). https://doi.org/10.1016/B978-0-08-046884-6.00223-2
Liu, M. F., S. Jiang, Z. Lu, Y. Li, and K. H. Young. “Physiological and Pathological Functions of Mammalian MicroRNAs.” In Comprehensive Toxicology: Second Edition, 2–14:427–46, 2010. https://doi.org/10.1016/B978-0-08-046884-6.00223-2.
Liu MF, Jiang S, Lu Z, Li Y, Young KH. Physiological and Pathological Functions of Mammalian MicroRNAs. In: Comprehensive Toxicology: Second Edition. 2010. p. 427–46.
Liu, M. F., et al. “Physiological and Pathological Functions of Mammalian MicroRNAs.” Comprehensive Toxicology: Second Edition, vol. 2–14, 2010, pp. 427–46. Scopus, doi:10.1016/B978-0-08-046884-6.00223-2.
Liu MF, Jiang S, Lu Z, Li Y, Young KH. Physiological and Pathological Functions of Mammalian MicroRNAs. Comprehensive Toxicology: Second Edition. 2010. p. 427–446.
DOI
Publication Date
January 1, 2010
Volume
2-14
Start / End Page
427 / 446